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PI3 Produits

(Peptidase Inhibitor 3, Skin-Derived (PI3))

Catégories

This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2008].

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Catégories PI3 en vedette

PI3 Anticorps

High quality antibodies with extensive validation data.

PI3 Kits ELISA

Reliable ELISA kits for a wide range of species.

PI3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PI3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application IHC
Validations
  • (4)
N° du produit ABIN7256144
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IP
Validations
  • (3)
N° du produit ABIN948256
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (3)
N° du produit ABIN6145588
Quantité 100 μL
Fiche technique Fiche technique

PI3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958441
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962602
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6720164
Quantité 1 kit
Fiche technique Fiche technique

PI3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314969
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293T Cells
Validations
  • (1)
N° du produit ABIN4369875
Quantité 2 μg
Fiche technique Fiche technique
Reactivity Human
Source Human Cells
Validations
N° du produit ABIN1097697
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PI3

Olewicz-Gawlik, Trzybulska, Graniczna, Kuznar-Kaminska, Katulska, Batura-Gabryel, Frydrychowicz, Danczak-Pazdrowska, Mozer-Lisewska: "Serum alarm antiproteases in systemic sclerosis patients." dans: Human immunology, Vol. 78, Issue 9, pp. 559-564, (2018) (PubMed).

Scott, Quach, Yang, Ardekani, Cabrera, Wilson, Messaoudi-Powers, Ghosh: "Matrix stiffness exerts biphasic control over monocyte-endothelial adhesion via Rho-mediated ICAM-1 clustering." dans: Integrative biology : quantitative biosciences from nano to macro, Vol. 8, Issue 8, pp. 869-78, (2016) (PubMed).

McGovern, Meinert, de Veer, Hollier, Parker, Upton: "Attenuated kallikrein-related peptidase activity disrupts desquamation and leads to stratum corneum thickening in human skin equivalent models." dans: The British journal of dermatology, (2016) (PubMed).

Liu, Chen, Wu, Chen, Zhang: "Neutrophil serine proteases and their endogenous inhibitors in coronary artery ectasia patients." dans: Anatolian journal of cardiology, Vol. 16, Issue 1, pp. 23-8, (2016) (PubMed).

Bermúdez-Humarán, Motta, Aubry, Kharrat, Rous-Martin, Sallenave, Deraison, Vergnolle, Langella: "Serine protease inhibitors protect better than IL-10 and TGF-? anti-inflammatory cytokines against mouse colitis when delivered by recombinant lactococci." dans: Microbial cell factories, Vol. 14, pp. 26, (2015) (PubMed).

Hellwig, Yoo, Reß, Andres, Braun, Schlegel, Wölfl: "Fulminant skin GvHD with a cytokine pattern resemblant of cytokine release syndrome successfully treated with multimodal immunosuppression including tocilizumab." dans: Pediatric blood & cancer, Vol. 62, Issue 11, pp. 2033-5, (2015) (PubMed).

Qundos, Hong, Tybring, Divers, Odeberg, Uhlen, Nilsson, Schwenk: "Profiling post-centrifugation delay of serum and plasma with antibody bead arrays." dans: Journal of proteomics, Vol. 95, pp. 46-54, (2013) (PubMed).

Gambichler, Demetriou, Terras, Bechara, Skrygan: "The impact of salt water soaks on biophysical and molecular parameters in psoriatic epidermis equivalents." dans: Dermatology (Basel, Switzerland), Vol. 223, Issue 3, pp. 230-8, (2012) (PubMed).

Wei, Hellström, Hellström: "Elafin selectively regulates the sensitivity of ovarian cancer cells to genotoxic drug-induced apoptosis." dans: Gynecologic oncology, Vol. 125, Issue 3, pp. 727-33, (2012) (PubMed).

Huh, Oono, Shirafuji, Akiyama, Arata, Sakaguchi, Huh, Iwatsuki: "Dynamic alteration of human beta-defensin 2 localization from cytoplasm to intercellular space in psoriatic skin." dans: Journal of molecular medicine (Berlin, Germany), Vol. 80, Issue 10, pp. 678-84, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à PI3

peptidase inhibitor 3 (PI3), peptidase inhibitor 3, skin-derived (SKALP) (PI3), cementoin, elafin, ESI, SKALP, trappin-2, TRAPPIN-2, WAP3, WFDC14

Protein level used designations for PI3

  • PI-3
  • WAP four-disulfide core domain 14
  • WAP four-disulfide core domain protein 14
  • elafin
  • elastase-specific inhibitor
  • pre-elafin
  • protease inhibitor 3, skin-derived (SKALP)
  • protease inhibitor WAP3
  • skin-derived antileukoproteinase
  • trappin-2
  • elafin preproprotein
  • peptidase inhibitor 3, skin-derived (SKALP)
  • TRAPPIN-2 protein
  • trappin ovine homolog
  • peptidase inhibitor 3, skin-derived
  • trappin 8
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