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PIAS1 Produits

(Protein Inhibitor of Activated STAT, 1 (PIAS1))

Catégories

This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq, Jul 2008].

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Catégories PIAS1 en vedette

PIAS1 Anticorps

High quality antibodies with extensive validation data.

PIAS1 Kits ELISA

Reliable ELISA kits for a wide range of species.

PIAS1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PIAS1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p), ICC
Validations
  • (1)
  • (6)
N° du produit ABIN3044474
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC (p), ICC
Validations
  • (10)
N° du produit ABIN3032369
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
N° du produit ABIN6264195
Quantité 100 μL
Fiche technique Fiche technique

PIAS1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969707
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381420
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method Quantitative
Validations
N° du produit ABIN1057747
Quantité 96 tests
Fiche technique Fiche technique

PIAS1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1314985
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314986
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314988
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PIAS1

Scortegagna, Berthon, Settas, Giannakou, Garcia, Li, James, Liddington, Vilches-Moure, Stratakis, Ronai: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." dans: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).

Chen, Tian, Mei, Wang, Yao, Zhang, Li, Wang, Zhang, Xie: "The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to radiation-induced lung fibrosis in mice." dans: Molecular immunology, Vol. 80, pp. 33-40, (2017) (PubMed).

Chen, Hsu, Ma, Tai, Lee: "CREB SUMOylation by the E3 ligase PIAS1 enhances spatial memory." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 29, pp. 9574-89, (2014) (PubMed).

Polyakova, Borman, Grimley, Vamathevan, Hayes, Solari: "Identification of novel interacting partners of Sirtuin6." dans: PLoS ONE, Vol. 7, Issue 12, pp. e51555, (2012) (PubMed).

Coppola, Parikh, Boulware, Blanck: "Substantially reduced expression of PIAS1 is associated with colon cancer development." dans: Journal of cancer research and clinical oncology, Vol. 135, Issue 9, pp. 1287-91, (2009) (PubMed).

Nishida, Yasuda: "PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription." dans: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41311-7, (2002) (PubMed).

Miyauchi, Yogosawa, Honda, Nishida, Yasuda: "Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes." dans: The Journal of biological chemistry, Vol. 277, Issue 51, pp. 50131-6, (2002) (PubMed).

Tan, Hall, Hamil, Grossman, Petrusz, French: "Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators." dans: The Journal of biological chemistry, Vol. 277, Issue 19, pp. 16993-7001, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à PIAS1

protein inhibitor of activated STAT 1 (PIAS1), protein inhibitor of activated STAT 1 (Pias1), protein inhibitor of activated STAT, 1 (Pias1), protein inhibitor of activated STAT, 1a (pias1a), protein inhibitor of activated STAT 1 L homeolog (pias1.L), 2900068C24Rik, Ddxbp1, DDXBP1, ddxbp1, GBP, gbp, GU/RH-II, pias, pias1-A, xPAIS1, xPIAS1, ZMIZ3, zmiz3

Protein level used designations for PIAS1

  • protein inhibitor of activated STAT, 1
  • DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1
  • DEAD/H box-binding protein 1
  • E3 SUMO-protein ligase PIAS1
  • protein inhibitor of activated STAT protein 1
  • AR interacting protein
  • RNA helicase II-binding protein
  • gu-binding protein
  • protein inhibitor of activated STAT-1
  • zinc finger, MIZ-type containing 3
  • SUMO E3 ligase
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