PIAS3 Produits
(Protein Inhibitor of Activated STAT, 3 (PIAS3))
Catégories
This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008].
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Catégories PIAS3 en vedette
PIAS3 Anticorps
High quality antibodies with extensive validation data.
PIAS3 Kits ELISA
Reliable ELISA kits for a wide range of species.
PIAS3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PIAS3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
N° du produit
ABIN6264198
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (8)
- (2)
N° du produit
ABIN1882116
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (7)
- (2)
N° du produit
ABIN1882115
Quantité
400 μL
Fiche technique
Fiche technique
PIAS3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958916
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1381422
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6206678
Quantité
96 tests
Fiche technique
Fiche technique
PIAS3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314993
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7407052
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Yeast
Validations
N° du produit
ABIN1475811
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PIAS3
: "Characterization of nuclear localization and SUMOylation of the ATBF1 transcription factor in epithelial cells." dans: PLoS ONE, Vol. 9, Issue 3, pp. e92746, (2014) (PubMed).: "SUMOylation of the GTPase Rac1 is required for optimal cell migration." dans: Nature cell biology, Vol. 12, Issue 11, pp. 1078-85, (2010) (PubMed).
: "The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2." dans: Journal of cellular biochemistry, Vol. 107, Issue 2, pp. 293-302, (2009) (PubMed).
: "Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 14, Issue 15, pp. 4694-704, (2008) (PubMed).
: "PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element." dans: The Journal of biological chemistry, Vol. 282, Issue 31, pp. 22335-43, (2007) (PubMed).
: "Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 12, Issue 22, pp. 6817-25, (2006) (PubMed).
: "ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3." dans: Biochemical and biophysical research communications, Vol. 314, Issue 1, pp. 97-103, (2004) (PubMed).
: "Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 1, pp. 99-104, (2004) (PubMed).
: "Down-regulation of SHP1 and up-regulation of negative regulators of JAK/STAT signaling in HTLV-1 transformed cell lines and freshly transformed human peripheral blood CD4+ T-cells." dans: Leukemia research, Vol. 28, Issue 1, pp. 71-82, (2003) (PubMed).
: "Molecular interactions between STAT3 and protein inhibitor of activated STAT3, and androgen receptor." dans: Biochemical and biophysical research communications, Vol. 306, Issue 2, pp. 610-5, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à PIAS3
protein inhibitor of activated STAT 3 (PIAS3), protein inhibitor of activated STAT 3 (pias3), protein inhibitor of activated STAT 3 (Pias3), protein inhibitor of activated STAT, 3 (Pias3), protein inhibitor of activated STAT 3 L homeolog (pias3.L), PIAS3, Pias3l, ZMIZ5Protein level used designations for PIAS3
- protein inhibitor of activated STAT, 3
- E3 SUMO-protein ligase PIAS3-like
- e3 SUMO-protein ligase PIAS3-like
- E3 SUMO-protein ligase PIAS3
- protein inhibitor of activated STAT protein 3
- zinc finger, MIZ-type containing 5
- KChAP
- potassium channel regulatory protein KChAP
- potassium channel-associated protein
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