PIK3C2A Produits
(Phosphoinositide-3-Kinase, Class 2, alpha Polypeptide (PIK3C2A))
Catégories
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008].
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Catégories PIK3C2A en vedette
PIK3C2A Anticorps
High quality antibodies with extensive validation data.
PIK3C2A Kits ELISA
Reliable ELISA kits for a wide range of species.
PIK3C2A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PIK3C2A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7431707
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), IF
Validations
- (4)
N° du produit
ABIN518885
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, ELISA
Validations
- (3)
N° du produit
ABIN185194
Quantité
100 μg
Fiche technique
Fiche technique
PIK3C2A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958551
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
N° du produit
ABIN1116456
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN2851450
Quantité
96 tests
Fiche technique
Fiche technique
PIK3C2A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315063
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN5509086
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7410745
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PIK3C2A
: "Mitotic Spindle Assembly and Genomic Stability in Breast Cancer Require PI3K-C2α Scaffolding Function. ..." dans: Cancer cell, Vol. 32, Issue 4, pp. 444-459.e7, (2017) (PubMed).: "miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 1, pp. 291-6, (2014) (PubMed).
: "PI3K/AKT pathway mediates induction of IL-1RA by TSH in fibrocytes: modulation by PTEN." dans: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 9, pp. 3363-72, (2014) (PubMed).
: "The SH3 domain of postsynaptic density 95 mediates inflammatory pain through phosphatidylinositol-3-kinase recruitment." dans: EMBO reports, Vol. 11, Issue 6, pp. 473-8, (2010) (PubMed).
: "Phosphoinositide 3-kinase C2alpha is activated upon smooth muscle cell migration and regulated by alpha(v)beta(3) integrin engagement." dans: Biochemical and biophysical research communications, Vol. 297, Issue 2, pp. 261-6, (2002) (PubMed).
: "The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles." dans: The Journal of biological chemistry, Vol. 275, Issue 16, pp. 11943-50, (2000) (PubMed).
: "Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain." dans: The Journal of biological chemistry, Vol. 271, Issue 23, pp. 13892-9, (1996) (PubMed).
Synonymes et noms alternatifs relatifs à PIK3C2A
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (PIK3C2A), phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (Pik3c2a), phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (pik3c2a), phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha S homeolog (pik3c2a.S), phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (LOC100548137), phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha (Pik3c2a), phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (pik3c2a), CPK, cpk, Cpk-m, PI3-K-C2(ALPHA), PI3-K-C2A, pi3-k-c2a, PI3KC2, sb:cb156, si:dkey-24l11.7, wu:fc02a04Protein level used designations for PIK3C2A
- C2-containing phosphatidylinositol kinase
- PI3K-C2-alpha
- PI3K-C2alpha
- phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
- phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha
- phosphoinositide 3-kinase-C2-alpha
- phosphoinositide-3-kinase, class 2, alpha polypeptide
- ptdIns-3-kinase C2 subunit alpha
- phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
- phosphoinositide-3-kinase, class 2 alpha polypeptide
- pi3-k-c2(alpha)
- Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide
- p170
- LOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
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