PIK3C2B Produits
(Phosphatidylinositol-4-Phosphate 3-Kinase, Catalytic Subunit Type 2 beta (PIK3C2B))
Catégories
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner. [provided by RefSeq, Jul 2008].
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Catégories PIK3C2B en vedette
PIK3C2B Anticorps
High quality antibodies with extensive validation data.
PIK3C2B Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PIK3C2B recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (8)
N° du produit
ABIN1500199
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
N° du produit
ABIN518887
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IHC (p), IF
Validations
- (4)
N° du produit
ABIN1500198
Quantité
100 μL
Fiche technique
Fiche technique
PIK3C2B recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315065
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7405546
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2728944
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PIK3C2B
: "PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets." dans: Molecular metabolism, Vol. 5, Issue 7, pp. 459-71, (2016) (PubMed).: "Association of Factor V Secretion with Protein Kinase B Signaling in Platelets from Horses with Atypical Equine Thrombasthenia." dans: Journal of veterinary internal medicine, Vol. 29, Issue 5, pp. 1387-94, (2016) (PubMed).
: "Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activity." dans: The Journal of biological chemistry, Vol. 273, Issue 49, pp. 33082-90, (1999) (PubMed).
Synonymes et noms alternatifs relatifs à PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta (Pik3c2b), phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta (PIK3C2B), C2-PI3KProtein level used designations for PIK3C2B
- nuclear cap binding protein subunit 2
- phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit beta
- phosphoinositide-3-kinase, class 2, beta polypeptide
- PI3K-C2-beta
- PI3K-C2beta
- PTDINS-3-kinase C2 beta
- phosphatidylinositol 3-kinase C2 domain-containing beta polypeptide
- phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
- phosphoinositide 3-kinase-C2-beta
- ptdIns-3-kinase C2 subunit beta
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