PITX2 Produits
(Paired-Like Homeodomain 2 (PITX2))
Catégories
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].
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Catégories PITX2 en vedette
PITX2 Anticorps
High quality antibodies with extensive validation data.
PITX2 Kits ELISA
Reliable ELISA kits for a wide range of species.
PITX2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PITX2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7163465
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (2)
- (3)
N° du produit
ABIN562251
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (1)
- (4)
N° du produit
ABIN2776373
Quantité
100 μL
Fiche technique
Fiche technique
PITX2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Chicken
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6231839
Quantité
96 tests
Fiche technique
Fiche technique
PITX2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315183
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315189
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315185
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PITX2
: "Functional corneal endothelium derived from corneal stroma stem cells of neural crest origin by retinoic acid and Wnt/?-catenin signaling." dans: Stem cells and development, Vol. 22, Issue 5, pp. 828-39, (2013) (PubMed).: "PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3." dans: Investigative ophthalmology & visual science, Vol. 52, Issue 10, pp. 7625-33, (2011) (PubMed).
: "Human PRKC apoptosis WT1 regulator is a novel PITX2-interacting protein that regulates PITX2 transcriptional activity in ocular cells." dans: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34829-38, (2009) (PubMed).
: "PITX2 gain-of-function induced defects in mouse forelimb development." dans: BMC developmental biology, Vol. 8, pp. 25, (2008) (PubMed).
: "Absence of PITX2, BARX1, and FOXC1 mutations in De Hauwere syndrome (Axenfeld-Rieger anomaly, hydrocephaly, hearing loss): a 25-year follow up." dans: American journal of medical genetics. Part A, Vol. 143A, Issue 11, pp. 1227-30, (2007) (PubMed).
: "Cytogenetically invisible microdeletions involving PITX2 in Rieger syndrome." dans: Clinical genetics, Vol. 72, Issue 5, pp. 464-70, (2007) (PubMed).
: "Variants conferring risk of atrial fibrillation on chromosome 4q25. ..." dans: Nature, Vol. 448, Issue 7151, pp. 353-7, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à PITX2
paired like homeodomain 2 (PITX2), paired-like homeodomain transcription factor 2 (Pitx2), paired-like homeodomain 2 (pitx2), paired-like homeodomain 2 (Pitx2), paired like homeodomain 2 S homeolog (pitx2.S), paired like homeodomain 2 (pitx2), paired like homeodomain 2 L homeolog (pitx2.L), paired like homeodomain 2 (Pitx2), 9430085M16Rik, ARP1, arp1, Brx1, brx1, Brx1a, Brx1b, IDG2, idg2, IGDS, igds, IGDS2, igds2, IHG2, ihg2, IRID2, irid2, Munc30, Otlx2, otlx2, pitx-2, pitx2, pitx2-A, Pitx2a, pitx2a, Pitx2b, Pitx2c, pitx2c, Pitx2cbeta, PTX2, Ptx2, ptx2, RGS, rgs, RIEG, Rieg, rieg, RIEG1, rieg1, RS, xpitx2, xPtx2, XPtx2b, zgc:110508Protein level used designations for PITX2
- ALL1-responsive protein ARP1
- all1-responsive gene 1
- homeobox protein PITX2
- paired-like homeodomain transcription factor 2
- pituitary homeobox 2
- rieg bicoid-related homeobox transcription factor 1
- solurshin
- BRX1 homeoprotein
- orthodenticle-like homeobox 2
- paired-like homeodomain transcription factor Munc 30
- paired-like homeodomain transcription factor 2a
- pitx2b
- homeodomain transcription factor 2
- rPtx2
- cPITX2
- transcription factor Pitx2
- homeodomain transcription factor Pitx2
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