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PKC alpha Produits

(Protein Kinase C, alpha (PKCa))
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008].

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Catégories PKC alpha en vedette

PKC alpha Anticorps

High quality antibodies with extensive validation data.

PKC alpha Kits ELISA

Reliable ELISA kits for a wide range of species.

PKC alpha Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PKC alpha recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p), PLA
Validations
  • (6)
N° du produit ABIN562379
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IF, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN391001
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IP, FACS, IF, ICC
Validations
  • (8)
N° du produit ABIN4904772
Quantité 100 μL
Fiche technique Fiche technique

PKC alpha recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969711
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969712
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969713
Quantité 96 tests
Fiche technique Fiche technique

PKC alpha recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316255
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Xenopus laevis
Source Insect Cells
Validations
N° du produit ABIN5509223
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7412596
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PKC alpha

Lin, Liang, Chen, Tsang, Chiou, Liu, Cheng, Lin, Liao, Huang, Chen, Tsai, Li: "Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 58, pp. 152893, (2019) (PubMed).

Grillo, McDevitt, Voas, Khan, Grillo, Stella: "Adenosine receptor expression in the adult zebrafish retina." dans: Purinergic signalling, Vol. 15, Issue 3, pp. 327-342, (2019) (PubMed).

Xie, Huo, Li, Dai, Xu, Yin: "Olfactory Ensheathing Cells Inhibit Gliosis in Retinal Degeneration by Downregulation of the Müller Cell Notch Signaling Pathway." dans: Cell transplantation, Vol. 26, Issue 6, pp. 967-982, (2018) (PubMed).

Hellmer, Clemons, Nawy, Ichinose: "A group I metabotropic glutamate receptor controls synaptic gain between rods and rod bipolar cells in the mouse retina." dans: Physiological reports, Vol. 6, Issue 20, pp. e13885, (2018) (PubMed).

Wu, Huang, Jiao, Ding, Zhang, Chen, Wang, Li, Huo: "Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells." dans: Oncotarget, Vol. 8, Issue 51, pp. 88630-88644, (2017) (PubMed).

Guimarães-Souza, Perche, Morgans, Duvoisin, Calaza: "Fragile X Mental Retardation Protein expression in the retina is regulated by light." dans: Experimental eye research, Vol. 146, pp. 72-82, (2016) (PubMed).

Yan-Fang, Zhi-Heng, Li-Xiao, Fang, Jun, Gang, Lan, Na-Na, Xiao-Juan, Li-Chao, Wen-Li, Pei-Fang, He, Guang-Hao, Yan-Hong, Yi-Ping, Yun-Yun, Hui-Ting, Yi, Mei-Fang, Lin, Jian, Shao-Yan, Xue-Ming, Xing et al.: "Molecular Mechanism of the Cell Death Induced by the Histone Deacetylase Pan Inhibitor LBH589 (Panobinostat) in Wilms Tumor Cells. ..." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0126566, (2016) (PubMed).

Gan, Wang, Zhao, Wu, Yang, Peng: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." dans: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).

Cheng, Gu, Yuan, Feng, Jia: "Suppression of A549 cell proliferation and metastasis by calycosin via inhibition of the PKC-α/ERK1/2 pathway: An in vitro investigation." dans: Molecular medicine reports, Vol. 13, Issue 4, pp. 3709-10, (2016) (PubMed).

Huang, Cheng, Su, Lin: "Syndecan-4 Promotes Epithelial Tumor Cells Spreading and Regulates the Turnover of PKC? Activity under Mechanical Stimulation on the Elastomeric Substrates." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 4, pp. 1291-1304, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à PKC alpha

protein kinase C alpha (PRKCA), protein kinase C, alpha L homeolog (prkca.L), protein kinase C, alpha (prkca), protein kinase C, alpha (Prkca), protein kinase C alpha (Prkca), AAG6, AI875142, im:7139045, LOC100219195, pkc-alpha, PKC-alpha, PKCA, Pkca, pkcalpha, PKRCA, PRKACA, si:dkey-8l19.1

Protein level used designations for PKC alpha

  • pkc-like 2
  • protein kinase C alpha type
  • protein kinase C, alpha
  • protein kinase C alpha type-like
  • PKC-A
  • aging-associated gene 6
  • PKC-alpha
  • protein kinase c-alpha
  • protein kinase, C alpha
  • protein kinase C alpha
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