Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

PKC gamma Produits

(Protein Kinase C, gamma (PRKCG))
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories PKC gamma en vedette

PKC gamma Anticorps

High quality antibodies with extensive validation data.

PKC gamma Kits ELISA

Reliable ELISA kits for a wide range of species.

PKC gamma Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PKC gamma recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (2)
N° du produit ABIN703285
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN391009
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN562388
Quantité 50 μL
Fiche technique Fiche technique

PKC gamma recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962223
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969722
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958929
Quantité 96 tests
Fiche technique Fiche technique

PKC gamma recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316265
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5509105
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7390385
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PKC gamma

Gan, Wang, Zhao, Wu, Yang, Peng: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." dans: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).

Shimobayashi, Wagner, Kapfhammer: "Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKC? Activity and Regulates Purkinje Cell Dendritic Growth." dans: Molecular neurobiology, (2015) (PubMed).

Zhang, Xu, Song, Yao, Ji: "Extracts from Salvia-Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity." dans: Journal of translational medicine, Vol. 12, pp. 236, (2015) (PubMed).

Ji, Hassler, Shimobayashi, Paka, Streit, Kapfhammer: "Increased protein kinase C gamma activity induces Purkinje cell pathology in a mouse model of spinocerebellar ataxia 14." dans: Neurobiology of disease, Vol. 70, pp. 1-11, (2014) (PubMed).

Verbeek, Knight, Harmison, Fischbeck, Howell: "Protein kinase C gamma mutations in spinocerebellar ataxia 14 increase kinase activity and alter membrane targeting." dans: Brain : a journal of neurology, Vol. 128, Issue Pt 2, pp. 436-42, (2005) (PubMed).

Uchino, Sakai, Kashiwagi, Shirai, Shinohara, Hirose, Iino, Yamamura, Saito: "Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC." dans: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 2254-61, (2004) (PubMed).

Kawakami, Kitaura, Yao, McHenry, Kawakami, Newton, Kang, Kato, Leitges, Rawlings, Kawakami: "A Ras activation pathway dependent on Syk phosphorylation of protein kinase C." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 16, pp. 9470-5, (2003) (PubMed).

Yabe, Sasaki, Chen, Raskind, Bird, Yamashita, Tsuji, Kikuchi, Tashiro: "Spinocerebellar ataxia type 14 caused by a mutation in protein kinase C gamma." dans: Archives of neurology, Vol. 60, Issue 12, pp. 1749-51, (2003) (PubMed).

van de Warrenburg, Verbeek, Piersma, Hennekam, Pearson, Knoers, Kremer, Sinke: "Identification of a novel SCA14 mutation in a Dutch autosomal dominant cerebellar ataxia family." dans: Neurology, Vol. 61, Issue 12, pp. 1760-5, (2003) (PubMed).

Saito, Shirai: "Protein kinase C gamma (PKC gamma): function of neuron specific isotype." dans: Journal of biochemistry, Vol. 132, Issue 5, pp. 683-7, (2002) (PubMed).

Synonymes et noms alternatifs relatifs à PKC gamma

protein kinase C gamma (PRKCG), protein kinase C, gamma (Prkcg), protein kinase C gamma type (LOC484316), protein kinase C gamma (Prkcg), PKC, PKC-gamma, PKCC, Pkcc, PKCG, PKCgamma, PKCI, Prkc, Prkcc, PRKCG, RATPKCI, SCA14

Protein level used designations for PKC gamma

  • protein kinase C, gamma
  • protein kinase C gamma type-like
  • protein kinase C gamma type
  • PKC-gamma
  • protein kinase C type I (gamma type)
  • PKC-delta
Vous êtes ici:
Support technique