PKC gamma Produits
(Protein Kinase C, gamma (PRKCG))
Catégories
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008].
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Catégories PKC gamma en vedette
PKC gamma Anticorps
High quality antibodies with extensive validation data.
PKC gamma Kits ELISA
Reliable ELISA kits for a wide range of species.
PKC gamma Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PKC gamma recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
N° du produit
ABIN703285
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
N° du produit
ABIN391009
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
N° du produit
ABIN562388
Quantité
50 μL
Fiche technique
Fiche technique
PKC gamma recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962223
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969722
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958929
Quantité
96 tests
Fiche technique
Fiche technique
PKC gamma recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316265
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN5509105
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7390385
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PKC gamma
: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." dans: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).: "Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKC? Activity and Regulates Purkinje Cell Dendritic Growth." dans: Molecular neurobiology, (2015) (PubMed).
: "Extracts from Salvia-Nelumbinis naturalis alleviate hepatosteatosis via improving hepatic insulin sensitivity." dans: Journal of translational medicine, Vol. 12, pp. 236, (2015) (PubMed).
: "Increased protein kinase C gamma activity induces Purkinje cell pathology in a mouse model of spinocerebellar ataxia 14." dans: Neurobiology of disease, Vol. 70, pp. 1-11, (2014) (PubMed).
: "Protein kinase C gamma mutations in spinocerebellar ataxia 14 increase kinase activity and alter membrane targeting." dans: Brain : a journal of neurology, Vol. 128, Issue Pt 2, pp. 436-42, (2005) (PubMed).
: "Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC." dans: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 2254-61, (2004) (PubMed).
: "A Ras activation pathway dependent on Syk phosphorylation of protein kinase C." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 16, pp. 9470-5, (2003) (PubMed).
: "Spinocerebellar ataxia type 14 caused by a mutation in protein kinase C gamma." dans: Archives of neurology, Vol. 60, Issue 12, pp. 1749-51, (2003) (PubMed).
: "Identification of a novel SCA14 mutation in a Dutch autosomal dominant cerebellar ataxia family." dans: Neurology, Vol. 61, Issue 12, pp. 1760-5, (2003) (PubMed).
: "Protein kinase C gamma (PKC gamma): function of neuron specific isotype." dans: Journal of biochemistry, Vol. 132, Issue 5, pp. 683-7, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à PKC gamma
protein kinase C gamma (PRKCG), protein kinase C, gamma (Prkcg), protein kinase C gamma type (LOC484316), protein kinase C gamma (Prkcg), PKC, PKC-gamma, PKCC, Pkcc, PKCG, PKCgamma, PKCI, Prkc, Prkcc, PRKCG, RATPKCI, SCA14Protein level used designations for PKC gamma
- protein kinase C, gamma
- protein kinase C gamma type-like
- protein kinase C gamma type
- PKC-gamma
- protein kinase C type I (gamma type)
- PKC-delta
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