PKC theta Produits
(Protein Kinase C, theta (PRKCQ))
Catégories
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008].
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Catégories PKC theta en vedette
PKC theta Anticorps
High quality antibodies with extensive validation data.
PKC theta Kits ELISA
Reliable ELISA kits for a wide range of species.
PKC theta Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PKC theta recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF, ICC
Validations
- (5)
N° du produit
ABIN6256401
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IP, IHC (f)
Validations
- (5)
- (4)
N° du produit
ABIN967739
Quantité
150 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (3)
N° du produit
ABIN7443020
Quantité
100 μL
Fiche technique
Fiche technique
PKC theta recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962224
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1116786
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1116787
Quantité
96 tests
Fiche technique
Fiche technique
PKC theta recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316274
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN5509109
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7415938
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PKC theta
: "Evidence of microglial activation following exposure to serum from first-onset drug-naïve schizophrenia patients." dans: Brain, behavior, and immunity, Vol. 67, pp. 364-373, (2018) (PubMed).: "Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation." dans: BMC cell biology, Vol. 14, pp. 39, (2013) (PubMed).
: "Atypical PKCzeta is involved in RhoA-dependent mitogenic signaling by the P2Y(12) receptor in C6 cells." dans: The FEBS journal, Vol. 273, Issue 8, pp. 1843-54, (2006) (PubMed).
: "Catalytic domain crystal structure of protein kinase C-theta (PKCtheta)." dans: The Journal of biological chemistry, Vol. 279, Issue 48, pp. 50401-9, (2004) (PubMed).
: "Characterization of TCR-induced phosphorylation of PKCtheta in primary murine lymphocytes." dans: Molecular immunology, Vol. 40, Issue 13, pp. 931-42, (2004) (PubMed).
: "Association of CBFA2 mutation with decreased platelet PKC-theta and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in ..." dans: Blood, Vol. 103, Issue 3, pp. 948-54, (2004) (PubMed).
: "Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta." dans: The Journal of biological chemistry, Vol. 279, Issue 18, pp. 18623-32, (2004) (PubMed).
: "Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway." dans: The Journal of biological chemistry, Vol. 279, Issue 21, pp. 22118-23, (2004) (PubMed).
: "Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes." dans: Molecular biology of the cell, Vol. 15, Issue 6, pp. 2932-42, (2004) (PubMed).
: "Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis." dans: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28315-9, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à PKC theta
protein kinase C theta (PRKCQ), protein kinase C eta (PRKCH), protein kinase C, theta (Prkcq), protein kinase C theta (Prkcq), A130035A12Rik, AW494342, nPKC-theta, PKC-0, PKC-theta, Pkcq, PKCtheta, PRKCTProtein level used designations for PKC theta
- protein kinase C theta type
- PKC theta
- nPKC-theta
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