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PKD2 Produits

(Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011].

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Catégories PKD2 en vedette

PKD2 Anticorps

High quality antibodies with extensive validation data.

PKD2 Kits ELISA

Reliable ELISA kits for a wide range of species.

PKD2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PKD2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, WB, IF
Validations
  • (4)
N° du produit ABIN562252
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
N° du produit ABIN7163836
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC
Validations
  • (2)
N° du produit ABIN3182238
Quantité 100 μL
Fiche technique Fiche technique

PKD2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969449
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380357
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN5595162
Quantité 96 tests
Fiche technique Fiche technique

PKD2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315202
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
N° du produit ABIN5509111
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3114704
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PKD2

Zheng, Shen, Hu, Roy, Yang, Wang, Zhang, King, Sergi, Liu, Cordat, Tang, Cao, Ali, Chen: "Far Upstream Element-Binding Protein 1 Binds the 3' Untranslated Region of PKD2 and Suppresses Its Translation." dans: Journal of the American Society of Nephrology : JASN, Vol. 27, Issue 9, pp. 2645-57, (2016) (PubMed).

Gargalionis, Korkolopoulou, Farmaki, Piperi, Dalagiorgou, Adamopoulos, Levidou, Saetta, Fragkou, Tsioli, Kiaris, Zizi-Serbetzoglou, Karavokyros, Papavassiliou, Tsavaris, Patsouris, Basdra et al.: "Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer. ..." dans: International journal of cancer. Journal international du cancer, Vol. 136, Issue 7, pp. 1515-27, (2015) (PubMed).

Varela, Piperi, Sigala, Agrogiannis, Davos, Andri, Manopoulos, Tsangaris, Basdra, Papavassiliou: "Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity." dans: Scientific reports, Vol. 5, pp. 13461, (2015) (PubMed).

Fencl, Janda, Bláhová, Hríbal, Stekrová, Puchmajerová, Seeman: "Genotype-phenotype correlation in children with autosomal dominant polycystic kidney disease." dans: Pediatric nephrology (Berlin, Germany), Vol. 24, Issue 5, pp. 983-9, (2009) (PubMed).

Stayner, Zhou: "Polycystin channels and kidney disease." dans: Trends in pharmacological sciences, Vol. 22, Issue 11, pp. 543-6, (2001) (PubMed).

Watnick, He, Wang, Liang, Parfrey, Hefferton, St George-Hyslop, Germino, Pei: "Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations." dans: Nature genetics, Vol. 25, Issue 2, pp. 143-4, (2000) (PubMed).

Lehtonen, Ora, Olkkonen, Geng, Zerial, Somlo, Lehtonen: "In vivo interaction of the adapter protein CD2-associated protein with the type 2 polycystic kidney disease protein, polycystin-2." dans: The Journal of biological chemistry, Vol. 275, Issue 42, pp. 32888-93, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à PKD2

polycystin 2, transient receptor potential cation channel (PKD2), polycystic kidney disease 2 (Pkd2), polycystin 2, transient receptor potential cation channel (Pkd2), Polycystin-2 (pkd-2), polycystin 2, transient receptor potential cation channel L homeolog (pkd2.L), polycystic kidney disease 2 (pkd2), APKD2, C030034P18Rik, Cup, Pc-2, PC2, pkd2, PKD2L1, PKD4, RGD1559992, TRPP2, trpp2

Protein level used designations for PKD2

  • R48321
  • autosomal dominant polycystic kidney disease type II protein
  • polycystin-2
  • polycystwin
  • transient receptor potential cation channel, subfamily P, member 2
  • polycystic kidney disease 2 protein homolog
  • polycystin 2
  • polycystic kidney disease 2 homolog
  • polycystic kidney disease 2 membrane protein
  • cation channel
  • polycystic kidney disease 2 (autosomal dominant) L homeolog
  • polycystin-2-like
  • Curly up
  • Polycystic kidney disease 2 protein homolog
  • TRPP2
  • Transient receptor potential cation channel subfamily P member 2
  • cup
  • curly up
  • transient receptor potential cation channel subfamily P member 2
  • polycystic kidney disease 2 (autosomal dominant)
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