PKLR Produits
(Pyruvate Kinase, Liver and RBC (PKLR))
Catégories
The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories PKLR en vedette
PKLR Anticorps
High quality antibodies with extensive validation data.
PKLR Kits ELISA
Reliable ELISA kits for a wide range of species.
PKLR Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PKLR recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7431302
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7431305
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (4)
N° du produit
ABIN950030
Quantité
100 μL
Fiche technique
Fiche technique
PKLR recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
N° du produit
ABIN6959012
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959013
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959014
Quantité
96 tests
Fiche technique
Fiche technique
PKLR recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7275451
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315223
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315225
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PKLR
: "Time-Dependent Changes in the Serum Levels of Neurobiochemical Factors After Acute Methadone Overdose in Adolescent Male Rat." dans: Cellular and molecular neurobiology, (2020) (PubMed).: "Contact system activation and high thrombin generation in hyperthyroidism." dans: European journal of endocrinology, Vol. 176, Issue 5, pp. 583-589, (2017) (PubMed).
: "The effects of PGC-1α on the proliferation and energy metabolism of malignant endometrial cancer cells." dans: OncoTargets and therapy, Vol. 8, pp. 769-74, (2015) (PubMed).
: "Association of C-terminal region of phosphoglycerate mutase with glycolytic complex regulates energy production in cancer cells." dans: Journal of cellular physiology, Vol. 227, Issue 6, pp. 2613-21, (2012) (PubMed).
: "Proteomic analyses of transgenic LQT1 and LQT2 rabbit hearts elucidate an increase in expression and activity of energy producing enzymes." dans: Journal of proteomics, Vol. 75, Issue 17, pp. 5254-65, (2012) (PubMed).
: "The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cells." dans: Molecular biology of the cell, Vol. 21, Issue 19, pp. 3449-58, (2010) (PubMed).
: "Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians." dans: Diabetes, Vol. 51, Issue 9, pp. 2861-5, (2002) (PubMed).
: "Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia." dans: The Journal of biological chemistry, Vol. 277, Issue 26, pp. 23807-14, (2002) (PubMed).
: "PKLR- GBA region shows almost complete linkage disequilibrium over 70 kb in a set of worldwide populations." dans: Human genetics, Vol. 110, Issue 6, pp. 532-44, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à PKLR
pyruvate kinase L/R (PKLR), pyruvate kinase, liver and RBC (Pklr), pyruvate kinase L/R (pklr), pyruvate kinase, liver and RBC L homeolog (pklr.L), pyruvate kinase, liver and RBC (pklr), pyruvate kinase, liver and RBC (PKLR), pyruvate kinase liver and red blood cell (Pklr), pyruvate kinase L/R (Pklr), pyruvate kinase PKLR-like (LOC100621940), Pk-1, PK1, pk1, Pk1, PKL, Pklg, PKLR, pklr, PKR, PKRL, R-PK, RPK, wu:fd15e01, wu:fi37e08Protein level used designations for PKLR
- R-type/L-type pyruvate kinase
- pyruvate kinase 1
- pyruvate kinase PKLR
- pyruvate kinase isozyme R/L
- pyruvate kinase isozymes L/R
- pyruvate kinase isozymes R/L
- pyruvate kinase type L
- pyruvate kinase, liver and blood cell
- red cell/liver pyruvate kinase
- L-PK
- pyruvate kinase, liver and red blood cell
- pyruvate kinase, liver and RBC
- Pyruvate kinase isozyme R
- Pyruvate kinase isozymes R/L
- pyruvate kinase isozymes R/L-like
- secretory carrier-associated membrane protein 3-like
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