PKM2 Produits
(Pyruvate Kinase M2 (PKM2))
Catégories
This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011].
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Catégories PKM2 en vedette
PKM2 Anticorps
High quality antibodies with extensive validation data.
PKM2 Kits ELISA
Reliable ELISA kits for a wide range of species.
PKM2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PKM2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (10)
N° du produit
ABIN7438913
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (13)
N° du produit
ABIN7432133
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, IHC (p), IF
Validations
- (1)
- (5)
N° du produit
ABIN391053
Quantité
200 μL
Fiche technique
Fiche technique
PKM2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (6)
N° du produit
ABIN6574169
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6960739
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960740
Quantité
96 tests
Fiche technique
Fiche technique
PKM2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315230
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315227
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124724
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PKM2
: "Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway." dans: Cell reports, Vol. 30, Issue 6, pp. 1780-1797.e6, (2020) (PubMed).: "A pathogen-derived effector modulates host glucose metabolism by arginine GlcNAcylation of HIF-1α protein." dans: PLoS pathogens, Vol. 14, Issue 8, pp. e1007259, (2019) (PubMed).
: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." dans: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).
: "PKM2 promotes cell migration and inhibits autophagy by mediating PI3K/AKT activation and contributes to the malignant development of gastric cancer." dans: Scientific reports, Vol. 7, Issue 1, pp. 2886, (2018) (PubMed).
: "Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis." dans: Oncotarget, Vol. 9, Issue 25, pp. 17430-17442, (2018) (PubMed).
: "A Novel Combination RNAi toward Warburg Effect by Replacement with miR-145 and Silencing of PTBP1 Induces Apoptotic Cell Death in Bladder Cancer Cells." dans: International journal of molecular sciences, Vol. 18, Issue 1, (2017) (PubMed).
: "MiR-145 negatively regulates Warburg effect by silencing KLF4 and PTBP1 in bladder cancer cells." dans: Oncotarget, Vol. 8, Issue 20, pp. 33064-33077, (2017) (PubMed).
: "Specific tumor-derived CCL2 mediated by pyruvate kinase M2 in colorectal cancer cells contributes to macrophage recruitment in tumor microenvironment." dans: Tumour biology, Vol. 39, Issue 3, pp. 1010428317695962, (2017) (PubMed).
: "Enhanced aerobic glycolysis of nasopharyngeal carcinoma cells by Epstein-Barr virus latent membrane protein 1." dans: Experimental cell research, Vol. 359, Issue 1, pp. 94-100, (2017) (PubMed).
: "M2 isoform of pyruvate kinase (PKM2) is upregulated in Kazakh's ESCC and promotes proliferation and migration of ESCC cells." dans: Tumour biology, Vol. 37, Issue 2, pp. 2665-72, (2016) (PubMed).
Synonymes et noms alternatifs relatifs à PKM2
pyruvate kinase M1/2 (PKM), pyruvate kinase, muscle (Pkm), pyruvate kinase, muscle (PKM), AA414905, AL024370, AL024424, CTHBP, OIP3, Pk-2, Pk-3, PK3, Pk3, PKM, PKM2, Pkm2, PKM12, TCB, THBP1Protein level used designations for PKM2
- OIP-3
- OPA-interacting protein 3
- PK, muscle type
- cytosolic thyroid hormone-binding protein
- p58
- pyruvate kinase 2/3
- pyruvate kinase PKM
- pyruvate kinase isozymes M1/M2
- pyruvate kinase muscle isozyme
- thyroid hormone-binding protein 1
- thyroid hormone-binding protein, cytosolic
- tumor M2-PK
- pyruvate kinase 3
- ATP:pyruvate 2-o-phosphotransferase
- Pyruvate kinase isozymes M1/M2
- Pyruvate kinase muscle isozyme
- Pyruvate kinase PKM
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