PLAT Produits
(Plasminogen Activator, Tissue (PLAT))
Catégories
This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding\; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories PLAT en vedette
PLAT Anticorps
High quality antibodies with extensive validation data.
PLAT Kits ELISA
Reliable ELISA kits for a wide range of species.
PLAT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PLAT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (6)
N° du produit
ABIN2855635
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN1860843
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7431908
Quantité
100 μL
Fiche technique
Fiche technique
PLAT recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (5)
N° du produit
ABIN6730952
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6958608
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969358
Quantité
96 tests
Fiche technique
Fiche technique
PLAT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN2566071
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN6388054
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
N° du produit
ABIN6387935
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PLAT
: "Intravenous Glu-plasminogen attenuates cholesterol crystal embolism-induced thrombotic angiopathy, acute kidney injury and kidney infarction." dans: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, (2022) (PubMed).: "Urokinase receptor and tissue plasminogen activator as immediate-early genes in pentylenetetrazole-induced seizures in the mouse brain." dans: The European journal of neuroscience, Vol. 51, Issue 7, pp. 1559-1572, (2020) (PubMed).
: "Sodium aescinate significantly suppress postoperative peritoneal adhesion by inhibiting the RhoA/ROCK signaling pathway." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 69, pp. 153193, (2020) (PubMed).
: "Low-Intensity Focused Ultrasound-Responsive Phase-Transitional Nanoparticles for Thrombolysis without Vascular Damage: A Synergistic Nonpharmaceutical Strategy." dans: ACS nano, Vol. 13, Issue 3, pp. 3387-3403, (2019) (PubMed).
: "Mechanical Adaptability of the MMP-Responsive Film Improves the Functionality of Endothelial Cell Monolayer." dans: Advanced healthcare materials, Vol. 6, Issue 14, (2018) (PubMed).
: "Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits." dans: Biochimica et biophysica acta, Vol. 1863, Issue 4, pp. 991-1001, (2017) (PubMed).
: "Cytokine and estrogen stimulation of endothelial cells augments activation of the prekallikrein-high molecular weight kininogen complex: Implications for hereditary angioedema." dans: The Journal of allergy and clinical immunology, Vol. 140, Issue 1, pp. 170-176, (2017) (PubMed).
: "Alteration of Hemostatic Parameters in Patients with Different Levels of Subclinical Hypothyroidism and the Effect of L-thyroxine Treatment." dans: Annals of clinical and laboratory science, Vol. 47, Issue 1, pp. 29-35, (2017) (PubMed).
: "Defective Platelet Activation and Bleeding Complications upon Cholestasis in Mice." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 6, pp. 2133-2149, (2017) (PubMed).
: "Skin infections are eliminated by cooperation of the fibrinolytic and innate immune systems." dans: Science immunology, Vol. 2, Issue 15, (2017) (PubMed).
Synonymes et noms alternatifs relatifs à PLAT
plasminogen activator, tissue type (PLAT), plasminogen activator, tissue (Plat), plasminogen activator, tissue type (Plat), plasminogen activator, tissue (PLAT), plasminogen activator, tissue (plat), plasminogen activator, tissue type (plat), chromosome 20 open reading frame 181 (C20orf181), plasminogen activator, tissue L homeolog (plat.L), AU020998, AW212668, D8Ertd2e, PATISS, Plat, plat, T-PA, t-pa, TPA, tPA, tpaProtein level used designations for PLAT
- alteplase
- plasminogen activator, tissue type
- reteplase
- t-plasminogen activator
- tissue plasminogen activator (t-PA)
- tissue-type plasminogen activator
- t-PA
- tissue plasminogen activator
- tPA
- T-plasminogen activator
- plasminogen activator, tissue
- tissue-type plasminogen activator-like
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