PLAUR Produits
(Plasminogen Activator, Urokinase Receptor (PLAUR))
Catégories
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008].
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Catégories PLAUR en vedette
PLAUR Anticorps
High quality antibodies with extensive validation data.
PLAUR Kits ELISA
Reliable ELISA kits for a wide range of species.
PLAUR Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PLAUR recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
N° du produit
ABIN7431179
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, FACS, IF (cc)
Validations
- (5)
N° du produit
ABIN675443
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
N° du produit
ABIN7193215
Quantité
100 μL
Fiche technique
Fiche technique
PLAUR recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
N° du produit
ABIN6958616
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6958617
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969366
Quantité
96 tests
Fiche technique
Fiche technique
PLAUR recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
N° du produit
ABIN7275406
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7275402
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7275407
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PLAUR
: "uPAR isoform 2 forms a dimer and induces severe kidney disease in mice." dans: The Journal of clinical investigation, Vol. 130, (2019) (PubMed).: "Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease." dans: Nature medicine, Vol. 23, Issue 1, pp. 100-106, (2017) (PubMed).
: "Cleavage of the urokinase receptor (uPAR) on oral cancer cells: regulation by transforming growth factor - β1 (TGF-β1) and potential effects on migration and invasion." dans: BMC cancer, Vol. 17, Issue 1, pp. 350, (2017) (PubMed).
: "Urokinase-type Plasminogen Activator (uPA) Binding to the uPA Receptor (uPAR) Promotes Axonal Regeneration in the Central Nervous System." dans: The Journal of biological chemistry, Vol. 292, Issue 7, pp. 2741-2753, (2017) (PubMed).
: "Clinical value of soluble urokinase-type plasminogen activator receptor in the diagnosis, prognosis, and therapeutic guidance of sepsis." dans: The American journal of emergency medicine, Vol. 34, Issue 3, pp. 375-80, (2016) (PubMed).
: "Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells. ..." dans: Nature communications, Vol. 7, pp. 11626, (2016) (PubMed).
: "A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease." dans: Kidney international, Vol. 87, Issue 3, pp. 564-74, (2015) (PubMed).
: "Tumour microenvironments induce expression of urokinase plasminogen activator receptor (uPAR) and concomitant activation of gelatinolytic enzymes." dans: PLoS ONE, Vol. 9, Issue 8, pp. e105929, (2015) (PubMed).
: "uPAR and cathepsin B-mediated compartmentalization of JNK regulates the migration of glioma-initiating cells." dans: Stem cell research, Vol. 12, Issue 3, pp. 716-29, (2014) (PubMed).
: "Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures." dans: Biophysical journal, Vol. 107, Issue 9, pp. 2101-11, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à PLAUR
plasminogen activator, urokinase receptor (Plaur), plasminogen activator, urokinase receptor (PLAUR), Cd87, CD87, Par, PLAUR, Plaur3, u-PAR, U-PAR, uPAR, UPAR, uPAR-2, uPAR-3, URKRProtein level used designations for PLAUR
- urokinase plasminogen activator receptor
- urokinase plasminogen activator surface receptor
- urokinase-type plasminogen activator receptor
- monocyte activation antigen Mo3
- u-plasminogen activator receptor form 2
- urokinase-type plasminogen activator (uPA) receptor
- U-PAR
- plasminogen activator urokinase receptor 3
- urinary plasminogen activator receptor 2
- urinary plasminogen activator receptor 3
- uPAR
- plasminogen activator, urokinase receptor
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