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PLOD1 Produits

(Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. [provided by RefSeq, Jul 2008].

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Catégories PLOD1 en vedette

PLOD1 Anticorps

High quality antibodies with extensive validation data.

PLOD1 Kits ELISA

Reliable ELISA kits for a wide range of species.

PLOD1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PLOD1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
  • (7)
N° du produit ABIN656585
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7441145
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p), EIA
Validations
  • (3)
N° du produit ABIN954205
Quantité 0.4 mL
Fiche technique Fiche technique

PLOD1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958786
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Chicken
Analytical Method
Validations
N° du produit ABIN1773428
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Sheep
Analytical Method
Validations
N° du produit ABIN1774652
Quantité 96 tests
Fiche technique Fiche technique

PLOD1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315447
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315445
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7406872
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PLOD1

Jover, Silvente, Marín, Martínez-González, Orriols, Martinez, Puche, Valdés, Rodriguez, Hernández-Romero: "Inhibition of enzymes involved in collagen cross-linking reduces vascular smooth muscle cell calcification." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 32, Issue 8, pp. 4459-4469, (2019) (PubMed).

Lindert, Cabral, Ausavarat, Tongkobpetch, Ludin, Barnes, Yeetong, Weis, Krabichler, Srichomthong, Makareeva, Janecke, Leikin, Röthlisberger, Rohrbach, Kennerknecht, Eyre, Suphapeetiporn, Giunta et al.: "MBTPS2 mutations cause defective regulated intramembrane proteolysis in X-linked osteogenesis imperfecta. ..." dans: Nature communications, Vol. 7, pp. 11920, (2018) (PubMed).

Heard, Besio, Weis, Rai, Hudson, Dimori, Zimmerman, Kamykowski, Hogue, Swain, Burdine, Mackintosh, Tackett, Suva, Eyre, Morello: "Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation." dans: PLoS genetics, Vol. 12, Issue 4, pp. e1006002, (2016) (PubMed).

Cabral, Ishikawa, Garten, Makareeva, Sargent, Weis, Barnes, Webb, Shaw, Ala-Kokko, Lacbawan, Högler, Leikin, Blank, Zimmerberg, Eyre, Yamada, Marini: "Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta." dans: PLoS genetics, Vol. 12, Issue 7, pp. e1006156, (2016) (PubMed).

Wågsäter, Paloschi, Hanemaaijer, Hultenby, Bank, Franco-Cereceda, Lindeman, Eriksson: "Impaired collagen biosynthesis and cross-linking in aorta of patients with bicuspid aortic valve." dans: Journal of the American Heart Association, Vol. 2, Issue 1, pp. e000034, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à PLOD1

procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (PLOD1), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (Plod1), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (PLOD1), procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (Plod1), procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (PLOD3), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 L homeolog (plod1.L), procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a (plod1a), 2410042F05Rik, AI854890, AV007929, EDS6, ik:tdsubs_rzpd609-29b19, LH, LH1, Lh1, LLH, PLOD, Plod, plod, plod1, procollagen-lysine, wu:fc29c10, wu:fc95g08, wu:fi18a05, zgc:152876

Protein level used designations for PLOD1

  • lysine hydroxylase
  • lysyl hydroxlase 1
  • procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1
  • procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
  • LH1
  • lysyl hydroxylase 1
  • procollagen-lysine 2-oxoglutarate 5-dioxygenase (lysine hydroxylase Ehlers-Danlos syndrome type VI)
  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI)
  • 2-oxoglutarate 5-dioxygenase 1
  • procollagen-lysine 5-dioxygenase
  • procollagen-lysine 2-oxoglutarate 5-dioxygenase 1
  • procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 L homeolog
  • fc95g08
  • fi18a05
  • lh1
  • procollagen lysine 2-oxoglutarate 5-dioxygenase 1
  • procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a
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