PMEPA1 Produits
(Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
Catégories
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
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Catégories PMEPA1 en vedette
PMEPA1 Anticorps
High quality antibodies with extensive validation data.
PMEPA1 Kits ELISA
Reliable ELISA kits for a wide range of species.
PMEPA1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PMEPA1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
IHC, StM
Validations
- (5)
N° du produit
ABIN6940417
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (8)
- (2)
N° du produit
ABIN566055
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, StM
Validations
- (3)
N° du produit
ABIN6940418
Quantité
100 μg
Fiche technique
Fiche technique
PMEPA1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1163040
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1163041
Quantité
96 tests
Fiche technique
Fiche technique
PMEPA1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315510
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3117192
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3129250
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PMEPA1
: "Mutation or loss of p53 differentially modifies TGF? action in ovarian cancer." dans: PLoS ONE, Vol. 9, Issue 2, pp. e89553, (2014) (PubMed).: "TGF-? induced TMEPAI/PMEPA1 inhibits canonical Smad signaling through R-Smad sequestration and promotes non-canonical PI3K/Akt signaling by reducing PTEN in triple negative breast cancer." dans: Genes & cancer, Vol. 5, Issue 9-10, pp. 320-36, (2014) (PubMed).
: "Identification of two distinct carcinoma-associated fibroblast subtypes with differential tumor-promoting abilities in oral squamous cell carcinoma." dans: Cancer research, Vol. 73, Issue 13, pp. 3888-901, (2013) (PubMed).
: "TMEPAI regulates EMT in lung cancer cells by modulating the ROS and IRS-1 signaling pathways." dans: Carcinogenesis, Vol. 34, Issue 8, pp. 1764-72, (2013) (PubMed).
: "High level expression of STAG1/PMEPA1 in an androgen-independent prostate cancer PC3 subclone." dans: Cellular & molecular biology letters, Vol. 12, Issue 3, pp. 370-7, (2012) (PubMed).
: "TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling." dans: Molecular cell, Vol. 37, Issue 1, pp. 123-34, (2010) (PubMed).
: "Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer." dans: Cancer research, Vol. 70, Issue 15, pp. 6377-83, (2010) (PubMed).
: "A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells." dans: The Journal of biological chemistry, Vol. 283, Issue 43, pp. 28988-95, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à PMEPA1
prostate transmembrane protein, androgen induced 1 (Pmepa1), prostate transmembrane protein, androgen induced 1 (PMEPA1), prostate transmembrane protein, androgen induced 1 (pmepa1), prostate transmembrane protein, androgen induced 1 L homeolog (pmepa1.L), 2210418I02Rik, AW455466, Erg1.2, N4wbp4, PMEPA1, STAG1, Stag1, Tmepai, TMEPAI, tmepai, zgc:92731Protein level used designations for PMEPA1
- transmembrane prostate androgen-induced protein
- transmembrane, prostate androgen induced RNA
- prostate transmembrane protein, androgen induced 1
- solid tumor-associated 1 protein
- NEDD4 WW domain-binding protein 4
- Nedd4 WW binding protein 4
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