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POFUT1 Produits

(Protein O-Fucosyltransferase 1 (POFUT1))

Catégories

This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories POFUT1 en vedette

POFUT1 Anticorps

High quality antibodies with extensive validation data.

POFUT1 Kits ELISA

Reliable ELISA kits for a wide range of species.

POFUT1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

POFUT1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7444553
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
  • (3)
N° du produit ABIN525219
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (2)
N° du produit ABIN7444556
Quantité 100 μL
Fiche technique Fiche technique

POFUT1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969730
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1134573
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1134574
Quantité 96 tests
Fiche technique Fiche technique

POFUT1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315608
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315606
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN2131215
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits POFUT1

Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." dans: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Takeuchi, Wong, Schneider, Freeze, Takeuchi, Berardinelli, Ito, Lee, Nelson, Haltiwanger: "Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features." dans: Glycobiology, Vol. 28, Issue 5, pp. 276-283, (2018) (PubMed).

Annani-Akollor, Wang, Fan, Liu, Padhiar, Zhang: "Downregulated protein O-fucosyl transferase 1 (Pofut1) expression exerts antiproliferative and antiadhesive effects on hepatocytes by inhibiting Notch signalling." dans: Biomedicine & pharmacotherapy, Vol. 68, Issue 6, pp. 785-90, (2014) (PubMed).

Stahl, Uemura, Ge, Shi, Tashima, Stanley: "Roles of Pofut1 and O-fucose in mammalian Notch signaling." dans: The Journal of biological chemistry, Vol. 283, Issue 20, pp. 13638-51, (2008) (PubMed).

Loriol, Dupuy, Rampal, Dlugosz, Haltiwanger, Maftah, Germot: "Molecular evolution of protein O-fucosyltransferase genes and splice variants." dans: Glycobiology, Vol. 16, Issue 8, pp. 736-47, (2006) (PubMed).

Shi, Stanley: "Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 9, pp. 5234-9, (2003) (PubMed).

Wang, Shao, Shi, Harris, Spellman, Stanley, Haltiwanger: "Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase." dans: The Journal of biological chemistry, Vol. 276, Issue 43, pp. 40338-45, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à POFUT1

protein O-fucosyltransferase 1 (POFUT1), protein O-fucosyltransferase 1 (pofut1), protein O-fucosyltransferase 1 (Pofut1), DDD2, fut12, FUT12, Fut12, mKIAA0180, o-fuc-t, O-Fuc-T, o-fuct-1, O-FucT-1, o-fut, O-FUT, OFUCT1, pofut1, zgc:110472

Protein level used designations for POFUT1

  • GDP-fucose protein O-fucosyltransferase 1
  • putative protein-O-fucosyltransferase
  • O-FucT-1
  • peptide-O-fucosyltransferase 1
  • protein-O-fucosyltransferase 1
  • protein-O-fucosyltransferase
  • protein O-fucosyltransferase 1
  • o-fucosyltransferase protein
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