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PON2 Produits

(Paraoxonase 2 (PON2))
This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

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Catégories PON2 en vedette

PON2 Anticorps

High quality antibodies with extensive validation data.

PON2 Kits ELISA

Reliable ELISA kits for a wide range of species.

PON2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PON2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (7)
N° du produit ABIN7440995
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (4)
N° du produit ABIN651946
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN2855759
Quantité 100 μL
Fiche technique Fiche technique

PON2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969140
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958392
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958393
Quantité 96 tests
Fiche technique Fiche technique

PON2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315744
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7397240
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7407646
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PON2

Devarajan, Su, Grijalva, Yalamanchi, Yalamanchi, Gao, Trost, Nwokedi, Farias-Eisner, Farias-Eisner, Fogelman, Reddy: "Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer." dans: Cell death & disease, Vol. 9, Issue 3, pp. 392, (2019) (PubMed).

Schwarzer, Fu, Morita, Whitt, Neely, Li, Machen: "Paraoxonase 2 serves a proapopotic function in mouse and human cells in response to the Pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-homoserine lactone." dans: The Journal of biological chemistry, Vol. 290, Issue 11, pp. 7247-58, (2015) (PubMed).

Parsanejad, Bourquard, Qu, Zhang, Huang, Rousseaux, Aleyasin, Irrcher, Callaghan, Vaillant, Kim, Slack, Mak, Reddy, Figeys, Park: "DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress." dans: PLoS ONE, Vol. 9, Issue 9, pp. e106601, (2014) (PubMed).

Devarajan, Bourquard, Hama, Navab, Grijalva, Morvardi, Clarke, Vergnes, Reue, Teiber, Reddy: "Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis." dans: Antioxidants & redox signaling, Vol. 14, Issue 3, pp. 341-51, (2011) (PubMed).

Shin: "Paraoxonase gene polymorphism in south-western Korean population." dans: Journal of Korean medical science, Vol. 24, Issue 4, pp. 561-6, (2009) (PubMed).

Rochu, Chabrière, Masson: "Human paraoxonase: a promising approach for pre-treatment and therapy of organophosphorus poisoning." dans: Toxicology, Vol. 233, Issue 1-3, pp. 47-59, (2007) (PubMed).

Mackness, Mackness: "Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?" dans: Free radical biology & medicine, Vol. 37, Issue 9, pp. 1317-23, (2004) (PubMed).

Reddy, Wadleigh, Grijalva, Ng, Hama, Gangopadhyay, Shih, Lusis, Navab, Fogelman: "Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 21, Issue 4, pp. 542-7, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à PON2

serum paraoxonase/arylesterase 2 (LOC100303695), paraoxonase 2 (PON2), paraoxonase 2 L homeolog (pon2.L), serum paraoxonase/arylesterase 2 (BDBG_00600), Serum paraoxonase/arylesterase 2 (pon2), paraoxonase 2 (Pon2), 6330405I24Rik, AI481612, MGC53915, pon1, PON2, pon2

Protein level used designations for PON2

  • A-esterase 2
  • Aromatic esterase 2
  • PON 2
  • Serum aryldialkylphosphatase 2
  • Serum paraoxonase/arylesterase 2
  • paraoxonase 2
  • celiac disease 2
  • serum paraoxonase/arylesterase 2-like
  • serum paraoxonase/arylesterase 2
  • aromatic esterase 2
  • paraoxonase nirs
  • serum aryldialkylphosphatase 2
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