PPM1F Produits
(Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))
Catégories
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008].
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Catégories PPM1F en vedette
PPM1F Anticorps
High quality antibodies with extensive validation data.
PPM1F Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PPM1F recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7165944
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (4)
N° du produit
ABIN564170
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
N° du produit
ABIN392883
Quantité
400 μL
Fiche technique
Fiche technique
PPM1F recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6232997
Quantité
96 tests
Fiche technique
Fiche technique
PPM1F recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315912
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315914
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124670
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PPM1F
: "Regulation of the multifunctional Ca2+/calmodulin-dependent protein kinase II by the PP2C phosphatase PPM1F in fibroblasts." dans: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24889-98, (2004) (PubMed).: "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages." dans: Nature medicine, Vol. 9, Issue 2, pp. 191-7, (2003) (PubMed).
: "The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family." dans: Current biology : CB, Vol. 12, Issue 4, pp. 317-21, (2002) (PubMed).
: "The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis." dans: The Journal of biological chemistry, Vol. 276, Issue 47, pp. 44193-202, (2001) (PubMed).
: "Molecular cloning of Ca2+/calmodulin-dependent protein kinase phosphatase." dans: Journal of biochemistry, Vol. 125, Issue 6, pp. 1022-8, (1999) (PubMed).
Synonymes et noms alternatifs relatifs à PPM1F
protein phosphatase, Mg2+/Mn2+ dependent 1F (PPM1F), protein phosphatase 1F (PP2C domain containing) (Ppm1f), protein phosphatase, Mg2+/Mn2+ dependent, 1F (Ppm1f), 1110021B16Rik, 4933427B07Rik, CAMKP, CaMKPase, FEM-2, hFEM-2, mKIAA0015, Popx2, POPX2Protein level used designations for PPM1F
- ca(2+)/calmodulin-dependent protein kinase phosphatase
- caM-kinase phosphatase
- calcium/calmodulin-dependent protein kinase phosphatase
- partner of PIX2
- protein phosphatase 1F
- Ca(2+)/calmodulin-dependent protein kinase phosphatase
- CaM-kinase phosphatase
- PP2C phosphatase
- partner of PIX 2
- protein fem-2 homolog
- protein phosphatase 1F (PP2C domain containing)
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