PPP2R1A Produits
(Protein Phosphatase 2, Regulatory Subunit A, alpha (PPP2R1A))
Catégories
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010].
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Catégories PPP2R1A en vedette
PPP2R1A Anticorps
High quality antibodies with extensive validation data.
PPP2R1A Kits ELISA
Reliable ELISA kits for a wide range of species.
PPP2R1A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PPP2R1A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IF, IP, IHC (p), ICC
Validations
- (1)
- (4)
N° du produit
ABIN2855322
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, PLA
Validations
- (3)
N° du produit
ABIN519115
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Drosophila melanogaster, Human, Monkey, Mouse, Rat
Application
WB, IF, FACS
Validations
- (3)
N° du produit
ABIN354403
Quantité
100 μL
Fiche technique
Fiche technique
PPP2R1A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6971299
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6231881
Quantité
96 tests
Fiche technique
Fiche technique
PPP2R1A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1316014
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124672
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2729487
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PPP2R1A
: "PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo." dans: Cells, Vol. 9, Issue 1, (2020) (PubMed).: "Clinicopathological effects of protein phosphatase 2, regulatory subunit A, alpha mutations in gastrointestinal stromal tumors." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 29, Issue 11, pp. 1424-1432, (2016) (PubMed).
: "PR65A phosphorylation regulates PP2A complex signaling." dans: PLoS ONE, Vol. 9, Issue 1, pp. e85000, (2014) (PubMed).
: "Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma." dans: Science (New York, N.Y.), Vol. 330, Issue 6001, pp. 228-31, (2010) (PubMed).
: "Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells." dans: Nature cell biology, Vol. 12, Issue 9, pp. 886-93, (2010) (PubMed).
: "Protein phosphatase 2A subunit gene haplotypes and proliferative breast disease modify breast cancer risk." dans: Cancer, Vol. 116, Issue 1, pp. 8-19, (2010) (PubMed).
: "Hypoxia-activated Smad3-specific dephosphorylation by PP2A." dans: The Journal of biological chemistry, Vol. 285, Issue 6, pp. 3740-9, (2010) (PubMed).
: "HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 6, pp. 2622-7, (2010) (PubMed).
: "A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair." dans: Neoplasia (New York, N.Y.), Vol. 11, Issue 10, pp. 1012-21, (2009) (PubMed).
: "Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation." dans: The Journal of biological chemistry, Vol. 282, Issue 12, pp. 9117-26, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à PPP2R1A
protein phosphatase 2 scaffold subunit Aalpha (PPP2R1A), protein phosphatase 2 scaffold subunit A alpha (Ppp2r1a), protein phosphatase 2 regulatory subunit A, alpha L homeolog (ppp2r1a.L), protein phosphatase 2 regulatory subunit A, alpha (ppp2r1a), protein phosphatase 2, regulatory subunit A, beta a (ppp2r1ba), serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (LOC583227), protein phosphatase 2, regulatory subunit A, alpha isoform (Ppp2r1a), protein phosphatase 2, regulatory subunit A, alpha (PPP2R1A), protein phosphatase 2, regulatory subunit A, alpha (Ppp2r1a), protein phosphatase 2 regulatory subunit A, alpha S homeolog (ppp2r1a.S), 6330556D22Rik, PP2A, PP2A-Aalpha, pp2a-aalpha, PP2AAALPHA, pp2aaalpha, ppp2r1a, ppp2r1a-a, ppp2r1a-b, PR65, PR65A, pr65a, wu:fa02h04, zgc:56296Protein level used designations for PPP2R1A
- PP2A subunit A isoform PR65-alpha
- PP2A subunit A isoform R1-alpha
- medium tumor antigen-associated 61 KDA protein
- protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
- serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform
- serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
- alpha isoform of regulatory subunit A, protein phosphatase 2
- protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform
- protein phosphatase 2 (formerly 2A), regulatory subunit A , alpha isoform
- protein phosphatase 2A 65 kDa regulatory subunit, alpha isoform
- protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
- medium tumor antigen-associated 61 kDa protein
- protein phosphatase 2, regulatory subunit A, alpha
- GLEAN_12508
- serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like
- protein phosphatase PP2A
- serine/threonine protein phosphatase A subunit type 2A
- protein phosphatase 2 regulatory subunit A, alpha S homeolog
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