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PPP2R2B Produits

(Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Catégories

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 66-78 copies in cases of SCA12. [provided by RefSeq, Jul 2008].

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Catégories PPP2R2B en vedette

PPP2R2B Anticorps

High quality antibodies with extensive validation data.

PPP2R2B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PPP2R2B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB
Validations
  • (4)
N° du produit ABIN519118
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IF, IHC
Validations
  • (3)
N° du produit ABIN7169246
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
N° du produit ABIN652541
Quantité 400 μL
Fiche technique Fiche technique

PPP2R2B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6231900
Quantité 96 tests
Fiche technique Fiche technique

PPP2R2B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316024
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316026
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316028
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PPP2R2B

Takashina, Kinoshita, Kikuchi, Shimizu, Sakakibara-Konishi, Oizumi, Nishimura, Dosaka-Akita: "Combined inhibition of EZH2 and histone deacetylases as a potential epigenetic therapy for non-small-cell lung cancer cells." dans: Cancer science, Vol. 107, Issue 7, pp. 955-62, (2016) (PubMed).

Synonymes et noms alternatifs relatifs à PPP2R2B

protein phosphatase 2 regulatory subunit Bbeta (PPP2R2B), protein phosphatase 2, regulatory subunit B, beta (Ppp2r2b), protein phosphatase 2 regulatory subunit B, beta L homeolog (ppp2r2b.L), protein phosphatase 2 regulatory subunit B, beta (ppp2r2b), protein phosphatase 2, regulatory subunit B, beta b (ppp2r2bb), protein phosphatase 2 regulatory subunit Bbeta (Ppp2r2b), 2900026H06Rik, 6330404L05Rik, B55BETA, E130009M08Rik, PP2A, PP2A-PR55B, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, ppp2r2b, PPP2R2B, ppp2r2b-a, ppp2r2c, Pppr2b2, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12, zgc:101861

Protein level used designations for PPP2R2B

  • PP2A subunit B isoform B55-beta
  • PP2A subunit B isoform PR55-beta
  • PP2A subunit B isoform R2-beta
  • PP2A, subunit B, B-beta isoform
  • protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
  • protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform
  • serine/threonine protein phosphatase 2A, 55 kDa regulatory subunit B, beta isoform
  • serine/threonine protein phosphatase 2A, neuronal isoform
  • serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform
  • BRbeta B-regulatory subunit of protein phosphatase 2A
  • PP2A subunit B isoform BRB
  • PP2A subunit B isoform beta
  • PP2A, subunit B, B55-beta isoform
  • PP2A, subunit B, BRB isoform
  • PP2A, subunit B, PR55-beta isoform
  • PP2A, subunit B, R2-beta isoform
  • phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
  • protein phosphatase 2A 55 kDa regulatory subunit, beta isoform
  • beta isoform of regulatory subunit B55, protein phosphatase 2
  • protein phosphatase-2A subunit-beta
  • protein phosphatase 2, regulatory subunit B, beta
  • serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform-like
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