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PPP2R4 Produits

(Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Catégories

Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories PPP2R4 en vedette

PPP2R4 Anticorps

High quality antibodies with extensive validation data.

PPP2R4 Kits ELISA

Reliable ELISA kits for a wide range of species.

PPP2R4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PPP2R4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application IHC, ELISA, ICC, FACS
Validations
  • (2)
  • (6)
N° du produit ABIN969557
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (5)
N° du produit ABIN519124
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application IF
Validations
  • (2)
  • (4)
N° du produit ABIN1682265
Quantité 100 μg
Fiche technique Fiche technique

PPP2R4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969737
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958945
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5674922
Quantité 96 tests
Fiche technique Fiche technique

PPP2R4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316044
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316042
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7406794
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PPP2R4

Jiang, Cao, Wang, Li, Liu, Lv, Li, Mi: "Cysteine transporter SLC3A1 promotes breast cancer tumorigenesis." dans: Theranostics, Vol. 7, Issue 4, pp. 1036-1046, (2017) (PubMed).

Wang, Gan, Wang, Wu, Cao, Zhu, Xu, Wang, Han, Li, Ye, Zhao, Mi: "Cancer-associated Fibroblasts Promote Irradiated Cancer Cell Recovery Through Autophagy." dans: EBioMedicine, Vol. 17, pp. 45-56, (2017) (PubMed).

Yoon, Jun, Park, Jun Yoo, Moon, Soon Baik, Kim, Kim, Kim, Koh, Taek Lee, You: "Optimal suppression of protein phosphatase 2A activity is critical for maintenance of human embryonic stem cell self-renewal." dans: Stem cells (Dayton, Ohio), Vol. 28, Issue 5, pp. 874-84, (2010) (PubMed).

Singh, Ye, Bucur, Zhu, Tanya Santos, Rabinovitz, Wei, Gao, Hahn, Khosravi-Far: "Protein phosphatase 2A reactivates FOXO3a through a dynamic interplay with 14-3-3 and AKT." dans: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1140-52, (2010) (PubMed).

Gushiken, Patel, Liu, Pradhan, Bergeron, Peng, Vijayan: "Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling." dans: The Journal of biological chemistry, Vol. 283, Issue 19, pp. 12862-9, (2008) (PubMed).

Fellner, Lackner, Hombauer, Piribauer, Mudrak, Zaragoza, Juno, Ogris: "A novel and essential mechanism determining specificity and activity of protein phosphatase 2A (PP2A) in vivo." dans: Genes & development, Vol. 17, Issue 17, pp. 2138-50, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à PPP2R4

protein phosphatase 2 phosphatase activator (PTPA), protein phosphatase 2 protein activator (Ptpa), protein phosphatase 2 phosphatase activator (Ptpa), protein phosphatase 2 phosphatase activator (ptpa), protein phosphatase 2 phosphatase activator L homeolog (ptpa.L), 2610042B21Rik, C77440, fc23d07, N28142, PP2A, pp2a, Ppp2r4, ppp2r4, ppp2r4.L, PR53, pr53, PTPA, ptpa, PTPRA, wu:fc23d07, zgc:92766

Protein level used designations for PPP2R4

  • PP2A phosphatase activator
  • PP2A subunit B' isoform PR53
  • phosphotyrosyl phosphatase activator
  • protein phosphatase 2A, regulatory subunit B' (PR 53)
  • serine/threonine-protein phosphatase 2A activator
  • serine/threonine-protein phosphatase 2A regulatory subunit B'
  • PP2A, subunit B', PR53 isoform
  • PTPA
  • serine/threonine-protein phosphatase 2A regulatory subunit 4
  • protein tyrosine phosphatase, receptor type, A
  • protein phosphatase 2 regulatory subunit 4
  • protein phosphatase 2A activator, regulatory subunit 4
  • protein phosphatase 2A regulatory subunit 4
  • protein phosphatase 2A, regulatory subunit B (PR 53)
  • protein phosphatase 2 phosphatase activator L homeolog
  • protein phosphatase 2A regulatory subunit 4 L homeolog
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