Premelanosome Protein Produits
(Premelanosome Protein (PMEL))
Catégories
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011].
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Catégories Premelanosome Protein en vedette
Premelanosome Protein Anticorps
High quality antibodies with extensive validation data.
Premelanosome Protein Kits ELISA
Reliable ELISA kits for a wide range of species.
Premelanosome Protein Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Premelanosome Protein recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Dog, Human, Monkey, Rat
Application
IHC, IF, WB, IHC (p)
Validations
- (17)
N° du produit
ABIN1500300
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, ELISA, StM, Coat
Validations
- (5)
N° du produit
ABIN6940589
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, IF, FACS, StM
Validations
- (4)
N° du produit
ABIN6940583
Quantité
100 μg
Fiche technique
Fiche technique
Premelanosome Protein recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6958713
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969484
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958714
Quantité
96 tests
Fiche technique
Fiche technique
Premelanosome Protein recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1320014
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN6964099
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7393823
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Premelanosome Protein
: "CXCL5 as Regulator of Neutrophil Function in Cutaneous Melanoma." dans: The Journal of investigative dermatology, Vol. 139, Issue 1, pp. 186-194, (2019) (PubMed).: "Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy. ..." dans: Immunity, Vol. 47, Issue 4, pp. 789-802.e9, (2017) (PubMed).
: "A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells." dans: Cancer research, Vol. 76, Issue 2, pp. 251-63, (2016) (PubMed).
: "ME20-S as a Potential Biomarker for the Evaluation of Uveal Melanoma." dans: Investigative ophthalmology & visual science, Vol. 56, Issue 12, pp. 7007-11, (2015) (PubMed).
: "MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment." dans: Nature communications, Vol. 6, pp. 8755, (2015) (PubMed).
: "Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma. ..." dans: Nature, Vol. 507, Issue 7490, pp. 109-13, (2014) (PubMed).
: "Artificial antigen-presenting cells expressing CD80, CD70, and 4-1BB ligand efficiently expand functional T cells specific to tumor-associated antigens." dans: Immunobiology, Vol. 219, Issue 8, pp. 583-92, (2014) (PubMed).
: "Mass spectrometry and imaging analysis of nanoparticle-containing vesicles provide a mechanistic insight into cellular trafficking." dans: ACS nano, Vol. 8, Issue 10, pp. 10077-88, (2014) (PubMed).
: "The Alarmin HMGN1 contributes to antitumor immunity and is a potent immunoadjuvant." dans: Cancer research, Vol. 74, Issue 21, pp. 5989-98, (2014) (PubMed).
: "BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 26, pp. 10658-63, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à Premelanosome Protein
premelanosome protein (PMEL), premelanosome protein (Pmel), premelanosome protein b (pmelb), premelanosome protein a (pmela), cb397, D10H12S53E, D12S53E, D12S53Eh, fdv, gp87, gp100, ME20, ME20-M, ME20M, MMP115, P1, P100, PMEL17, Pmel17, pmel17, RPE1, sb:cb397, SI, Si, SIL, SILV, Silv, silva, silver, silverb, wu:fc11g11, wu:fj24g11, zgc:136622Protein level used designations for Premelanosome Protein
- melanocyte protein PMEL
- melanocyte protein Pmel 17
- melanocyte protein mel 17
- melanocytes lineage-specific antigen GP100
- melanoma-associated ME20 antigen
- melanosomal matrix protein17
- silver locus protein homolog
- silver, mouse, homolog of
- melanocyte protein pmel 17
- silver locus protein
- retinal pigment epithelial-specific protein
- silver homolog
- 115 kDa melanosomal matrix protein
- PMEL17 protein
- melanosome matrix protein
- melanocyte protein 17
- premelanosomal protein
- fading vision
- melanosomal matrix protein
- silver homolog a
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