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Premelanosome Protein Produits

(Premelanosome Protein (PMEL))

Catégories

This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011].

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Catégories Premelanosome Protein en vedette

Premelanosome Protein Anticorps

High quality antibodies with extensive validation data.

Premelanosome Protein Kits ELISA

Reliable ELISA kits for a wide range of species.

Premelanosome Protein Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Premelanosome Protein recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Dog, Human, Monkey, Rat
Application IHC, IF, WB, IHC (p)
Validations
  • (17)
N° du produit ABIN1500300
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, ELISA, StM, Coat
Validations
  • (5)
N° du produit ABIN6940589
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application IHC, IF, FACS, StM
Validations
  • (4)
N° du produit ABIN6940583
Quantité 100 μg
Fiche technique Fiche technique

Premelanosome Protein recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958713
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969484
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958714
Quantité 96 tests
Fiche technique Fiche technique

Premelanosome Protein recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1320014
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN6964099
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7393823
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Premelanosome Protein

Forsthuber, Lipp, Andersen, Ebersberger, Graña-Castro, Ellmeier, Petzelbauer, Lichtenberger, Loewe: "CXCL5 as Regulator of Neutrophil Function in Cutaneous Melanoma." dans: The Journal of investigative dermatology, Vol. 139, Issue 1, pp. 186-194, (2019) (PubMed).

Glodde, Bald, van den Boorn-Konijnenberg, Nakamura, ODonnell, Szczepanski, Brandes, Eickhoff, Das, Shridhar, Hinze, Rogava, van der Sluis, Ruotsalainen, Gaffal, Landsberg, Ludwig, Wilhelm et al.: "Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy. ..." dans: Immunity, Vol. 47, Issue 4, pp. 789-802.e9, (2017) (PubMed).

Hölzel, Landsberg, Glodde, Bald, Rogava, Riesenberg, Becker, Jönsson, Tüting: "A Preclinical Model of Malignant Peripheral Nerve Sheath Tumor-like Melanoma Is Characterized by Infiltrating Mast Cells." dans: Cancer research, Vol. 76, Issue 2, pp. 251-63, (2016) (PubMed).

Bande, Santiago, Mera, Piulats, Blanco, Rodríguez-Álvarez, Capeans, Piñeiro, Pardo: "ME20-S as a Potential Biomarker for the Evaluation of Uveal Melanoma." dans: Investigative ophthalmology & visual science, Vol. 56, Issue 12, pp. 7007-11, (2015) (PubMed).

Riesenberg, Groetchen, Siddaway, Bald, Reinhardt, Smorra, Kohlmeyer, Renn, Phung, Aymans, Schmidt, Hornung, Davidson, Goding, Jönsson, Landsberg, Tüting, Hölzel: "MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment." dans: Nature communications, Vol. 6, pp. 8755, (2015) (PubMed).

Bald, Quast, Landsberg, Rogava, Glodde, Lopez-Ramos, Kohlmeyer, Riesenberg, van den Boorn-Konijnenberg, Hömig-Hölzel, Reuten, Schadow, Weighardt, Wenzel, Helfrich, Schadendorf, Bloch, Bianchi et al.: "Ultraviolet-radiation-induced inflammation promotes angiotropism and metastasis in melanoma. ..." dans: Nature, Vol. 507, Issue 7490, pp. 109-13, (2014) (PubMed).

Zeng, Su, Anderson, Sasada: "Artificial antigen-presenting cells expressing CD80, CD70, and 4-1BB ligand efficiently expand functional T cells specific to tumor-associated antigens." dans: Immunobiology, Vol. 219, Issue 8, pp. 583-92, (2014) (PubMed).

Hofmann, Tenzer, Bannwarth, Messerschmidt, Glaser, Schild, Landfester, Mailänder: "Mass spectrometry and imaging analysis of nanoparticle-containing vesicles provide a mechanistic insight into cellular trafficking." dans: ACS nano, Vol. 8, Issue 10, pp. 10077-88, (2014) (PubMed).

Wei, Yang, Tewary, Li, Li, Chen, Howard, Bustin, Oppenheim: "The Alarmin HMGN1 contributes to antitumor immunity and is a potent immunoadjuvant." dans: Cancer research, Vol. 74, Issue 21, pp. 5989-98, (2014) (PubMed).

Rochin, Hurbain, Serneels, Fort, Watt, Leblanc, Marks, De Strooper, Raposo, van Niel: "BACE2 processes PMEL to form the melanosome amyloid matrix in pigment cells." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 26, pp. 10658-63, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à Premelanosome Protein

premelanosome protein (PMEL), premelanosome protein (Pmel), premelanosome protein b (pmelb), premelanosome protein a (pmela), cb397, D10H12S53E, D12S53E, D12S53Eh, fdv, gp87, gp100, ME20, ME20-M, ME20M, MMP115, P1, P100, PMEL17, Pmel17, pmel17, RPE1, sb:cb397, SI, Si, SIL, SILV, Silv, silva, silver, silverb, wu:fc11g11, wu:fj24g11, zgc:136622

Protein level used designations for Premelanosome Protein

  • melanocyte protein PMEL
  • melanocyte protein Pmel 17
  • melanocyte protein mel 17
  • melanocytes lineage-specific antigen GP100
  • melanoma-associated ME20 antigen
  • melanosomal matrix protein17
  • silver locus protein homolog
  • silver, mouse, homolog of
  • melanocyte protein pmel 17
  • silver locus protein
  • retinal pigment epithelial-specific protein
  • silver homolog
  • 115 kDa melanosomal matrix protein
  • PMEL17 protein
  • melanosome matrix protein
  • melanocyte protein 17
  • premelanosomal protein
  • fading vision
  • melanosomal matrix protein
  • silver homolog a
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