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PRG2 Produits

(Bone Marrow Proteoglycan (PRG2))
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].

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Catégories PRG2 en vedette

PRG2 Anticorps

High quality antibodies with extensive validation data.

PRG2 Kits ELISA

Reliable ELISA kits for a wide range of species.

PRG2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PRG2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN3016204
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
N° du produit ABIN6264418
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN651919
Quantité 400 μL
Fiche technique Fiche technique

PRG2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965181
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975292
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6975668
Quantité 96 tests
Fiche technique Fiche technique

PRG2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316187
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Human Cells
Validations
N° du produit ABIN4370675
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Human Cells
Validations
N° du produit ABIN7318206
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PRG2

Singh, Chand, Banerjee, Agarwal, Raizada, Roy, Sopori: "Acetylcholinesterase Inhibitor Pyridostigmine Bromide Attenuates Gut Pathology and Bacterial Dysbiosis in a Murine Model of Ulcerative Colitis." dans: Digestive diseases and sciences, Vol. 65, Issue 1, pp. 141-149, (2020) (PubMed).

Roy, Ehrbar, Bohorova, Bohorov, Kim, Pauly, Whaley, Rong, Torres-Velez, Vitetta, Didier, Doyle-Meyers, Zeitlin, Mantis: "Rescue of rhesus macaques from the lethality of aerosolized ricin toxin." dans: JCI insight, Vol. 4, Issue 1, (2019) (PubMed).

Hashimoto, Kursewicz, Fayne, Nanda, Shah, Nattkemper, Yokozeki, Yosipovitch: "Pathophysiological mechanisms of itch in bullous pemphigoid." dans: Journal of the American Academy of Dermatology, (2019) (PubMed).

Hashimoto, Kursewicz, Fayne, Nanda, Shah, Nattkemper, Yokozeki, Yosipovitch: "Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages." dans: The Journal of investigative dermatology, (2019) (PubMed).

Ziemka-Nalecz, Janowska, Strojek, Jaworska, Zalewska, Frontczak-Baniewicz, Sypecka: "Impact of neonatal hypoxia-ischaemia on oligodendrocyte survival, maturation and myelinating potential." dans: Journal of cellular and molecular medicine, Vol. 22, Issue 1, pp. 207-222, (2018) (PubMed).

Costa, Trivellato, Rebech, Oliveira Dos Santos Maciel, Melo, Luvizotto, de Lima: "Eosinophilic inflammation in lymph nodes of dogs with visceral leishmaniasis." dans: Parasite immunology, Vol. 40, Issue 8, pp. e12567, (2018) (PubMed).

Gormley, Ona, Kapidzic, Garrido-Gomez, Zdravkovic, Fisher: "Preeclampsia: novel insights from global RNA profiling of trophoblast subpopulations." dans: American journal of obstetrics and gynecology, Vol. 217, Issue 2, pp. 200.e1-200.e17, (2017) (PubMed).

Bleyer, Curths, Dahlmann, Wichmann, Bauer, Moritz, Braun, Knauf, Kaup, Gruber-Dujardin: "Morphology and staining behavior of neutrophilic and eosinophilic granulocytes of the common marmoset (Callithrix jacchus)." dans: Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, (2016) (PubMed).

Vanheel, Vicario, Vanuytsel, Van Oudenhove, Martinez, Keita, Pardon, Santos, Söderholm, Tack, Farré: "Impaired duodenal mucosal integrity and low-grade inflammation in functional dyspepsia." dans: Gut, Vol. 63, Issue 2, pp. 262-71, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à PRG2

proteoglycan 2, bone marrow (Prg2), proteoglycan 2 (Prg2), proteoglycan 2, pro eosinophil major basic protein (PRG2), BMPG, MBP, MBP1, mMBP, mMBP-1

Protein level used designations for PRG2

  • BMPG
  • bone marrow proteoglycan
  • major basic protein 1
  • eosinophil major basic protein
  • bone-marrow proteoglycan
  • eosinophil granule major basic protein
  • natural killer cell activator
  • proteoglycan 2 preproprotein
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