PRKAB2 Produits
(Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
Catégories
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. [provided by RefSeq, Jul 2008].
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Catégories PRKAB2 en vedette
PRKAB2 Anticorps
High quality antibodies with extensive validation data.
PRKAB2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PRKAB2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
IHC, ELISA, FACS, ICC
Validations
- (7)
N° du produit
ABIN5611226
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
N° du produit
ABIN7262869
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
N° du produit
ABIN5611225
Quantité
100 μL
Fiche technique
Fiche technique
PRKAB2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124660
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316215
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316217
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PRKAB2
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." dans: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).
: "Effects of thyroid state on AMP-activated protein kinase and acetyl-CoA carboxylase expression in muscle." dans: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 93, Issue 6, pp. 2081-8, (2002) (PubMed).
: "Variant screening of PRKAB2, a type 2 diabetes mellitus susceptibility candidate gene on 1q in Pima Indians." dans: Molecular and cellular probes, Vol. 16, Issue 6, pp. 421-7, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog (prkab2.L), protein kinase AMP-activated non-catalytic subunit beta 2 (PRKAB2), protein kinase, AMP-activated, beta 2 non-catalytic subunit (PRKAB2), protein kinase, AMP-activated, beta 2 non-catalytic subunit (prkab2), protein kinase, AMP-activated, beta 2 non-catalytic subunit (Prkab2), protein kinase AMP-activated non-catalytic subunit beta 2 (Prkab2), 5730553K21Rik, AW049591, BB124140, DKFZp469M1118, MGC64365, prkab2, PRKAB2Protein level used designations for PRKAB2
- protein kinase, AMP-activated, beta 2 non-catalytic subunit
- AMP-activated protein kinase beta 2 non-catalytic subunit
- 5'-AMP-activated protein kinase subunit beta-2
- 5'-AMP-activated protein kinase, beta-2 subunit
- AMPK beta 2
- AMPK beta-2 chain
- AMPK subunit beta-2
- AMP-activated protein kinase beta-2 regulatory subunit
- AMPK beta-2
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