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PRKAG1 Produits

(Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))

Catégories

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Catégories PRKAG1 en vedette

PRKAG1 Anticorps

High quality antibodies with extensive validation data.

PRKAG1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PRKAG1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, ICC, FACS
Validations
  • (2)
  • (7)
N° du produit ABIN1724932
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7439723
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (4)
N° du produit ABIN7263301
Quantité 200 μL
Fiche technique Fiche technique

PRKAG1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN5853248
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316233
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2131292
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PRKAG1

Zaha, Young: "AMP-activated protein kinase regulation and biological actions in the heart." dans: Circulation research, Vol. 111, Issue 6, pp. 800-14, (2012) (PubMed).

Oliveira, Zhang, Solis, Isackson, Bellahcene, Yavari, Pinter, Davies, Ge, Ashrafian, Walker, Carling, Watkins, Casadei, Redwood: "AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes." dans: Circulation research, Vol. 110, Issue 9, pp. 1192-201, (2012) (PubMed).

Lin, Kiihl, Suhail, Liu, Chou, Kuang, Lu, Khor, Lin, Bader, Irizarry, Boeke: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." dans: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).

Greer, Oskoui, Banko, Maniar, Gygi, Gygi, Brunet: "The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor." dans: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 30107-19, (2007) (PubMed).

Minokoshi, Alquier, Furukawa, Kim, Lee, Xue, Mu, Foufelle, Ferré, Birnbaum, Stuck, Kahn: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." dans: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).

Hamilton, Stapleton, ODonnell, Kung, Dalal, Kemp, Witters: "An activating mutation in the gamma1 subunit of the AMP-activated protein kinase." dans: FEBS letters, Vol. 500, Issue 3, pp. 163-8, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à PRKAG1

protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog (prkag1.S), protein kinase, AMP-activated, gamma 1 non-catalytic subunit (prkag1), protein kinase AMP-activated non-catalytic subunit gamma 1 (PRKAG1), protein kinase AMP-activated non-catalytic subunit gamma 1 (Prkag1), protein kinase, AMP-activated, gamma 1 non-catalytic subunit (Prkag1), AA571379, AMPKG, BB036179, MGC68503, Prkaac, Prkga1, wu:fa94d09, wu:fd12h04, zgc:63896

Protein level used designations for PRKAG1

  • protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • 5'-AMP-activated protein kinase subunit gamma-1
  • AMPK-activated protein kinase gamma-1 subunit
  • AMP-activated protein kinase, noncatalytic gamma-1 subunit
  • 5'-AMP-activated protein kinase subunit gamma-1-like
  • 5'-AMP-activated protein kinase, gamma-1 subunit
  • AMPK gamma-1 chain
  • AMPK gamma1
  • AMPK subunit gamma-1
  • AMPKg
  • Protein kinase AMP-activated gamma
  • 38 kDa subunit
  • 5'-AMP-activated protein kinase gamma-1 subunit
  • AMP-activated protein kinase subunit gamma 1 (non-catalytic subunit)
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