PRKDC Produits
(Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
Catégories
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010].
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Catégories PRKDC en vedette
PRKDC Anticorps
High quality antibodies with extensive validation data.
PRKDC Kits ELISA
Reliable ELISA kits for a wide range of species.
PRKDC Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PRKDC recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, ICC
Validations
- (2)
- (5)
N° du produit
ABIN969366
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB, IF, IHC (p)
Validations
- (1)
- (5)
N° du produit
ABIN519209
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN6241643
Quantité
100 μL
Fiche technique
Fiche technique
PRKDC recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958940
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1381086
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Validations
N° du produit
ABIN1130280
Quantité
96 tests
Fiche technique
Fiche technique
PRKDC recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1316293
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7399958
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN5710145
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PRKDC
: "Interactome of the Autoimmune Risk Protein ANKRD55." dans: Frontiers in immunology, Vol. 10, pp. 2067, (2019) (PubMed).: "DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination." dans: Molecular cell, Vol. 65, Issue 4, pp. 671-684.e5, (2017) (PubMed).
: "The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites." dans: Nature communications, Vol. 8, pp. 15751, (2017) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." dans: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2." dans: Molecular biology of the cell, Vol. 28, Issue 1, pp. 192-200, (2016) (PubMed).
: "Identification of PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide) as an essential gene for colorectal cancer (CRCs) cells." dans: Gene, Vol. 584, Issue 1, pp. 90-6, (2016) (PubMed).
: "Quantification of the host response proteome after herpes simplex virus type 1 infection." dans: Journal of proteome research, Vol. 14, Issue 5, pp. 2121-42, (2015) (PubMed).
: "Mutual regulation between DNA-PKcs and Snail1 leads to increased genomic instability and aggressive tumor characteristics." dans: Cell death & disease, Vol. 4, pp. e517, (2013) (PubMed).
: "Accumulation of DNA damage-induced chromatin alterations in tissue-specific stem cells: the driving force of aging?" dans: PLoS ONE, Vol. 8, Issue 5, pp. e63932, (2013) (PubMed).
: "Beyond repair foci: DNA double-strand break repair in euchromatic and heterochromatic compartments analyzed by transmission electron microscopy." dans: PLoS ONE, Vol. 7, Issue 5, pp. e38165, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à PRKDC
protein kinase, DNA-activated, catalytic polypeptide (PRKDC), protein kinase, DNA-activated, catalytic polypeptide L homeolog (prkdc.L), DNA-dependent protein kinase catalytic subunit (LOC100633457), protein kinase, DNA activated, catalytic polypeptide (Prkdc), AI326420, AU019811, DNA-PKcs, DNA-PKCS, dna-pkcs, DNAPDcs, DNAPK, dnapk, DNPK1, dnpk1, DOXNPH, dxnph, HYRC, hyrc, HYRC1, hyrc1, p350, p460, PRKDC, prkdc-A, scid, slip, XRCC7, xrcc7Protein level used designations for PRKDC
- DNA-PK catalytic subunit
- DNA-dependent protein kinase catalytic subunit
- hyper-radiosensitivity of murine scid mutation, complementing 1
- p460
- protein kinase, DNA-activated, catalytic polypeptide
- DNA-PKcs
- protein kinase catalytic subunit (DNA-dependent protein kinase)
- DNA-activated protein kinase catalytic polypeptide
- DNA-dependent protein kinase catalytic subunit-like
- doxorubicin nephropathy
- severe combined immunodeficiency
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