Protein Phosphatase 4, Regulatory Subunit 2 Produits
(Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
Catégories
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair (By similarity). Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage- dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair (By similarity).
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Catégories Protein Phosphatase 4, Regulatory Subunit 2 en vedette
Protein Phosphatase 4, Regulatory Subunit 2 Anticorps
High quality antibodies with extensive validation data.
Protein Phosphatase 4, Regulatory Subunit 2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Protein Phosphatase 4, Regulatory Subunit 2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse, Rat
Application
IHC, IF
Validations
- (4)
N° du produit
ABIN7075284
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, ICC
Validations
- (2)
N° du produit
ABIN6257426
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB
Validations
- (2)
N° du produit
ABIN1500387
Quantité
100 μL
Fiche technique
Fiche technique
Protein Phosphatase 4, Regulatory Subunit 2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6206801
Quantité
96 tests
Fiche technique
Fiche technique
Protein Phosphatase 4, Regulatory Subunit 2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rabbit
Source
Yeast
Validations
N° du produit
ABIN1473073
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Xenopus laevis
Source
Yeast
Validations
N° du produit
ABIN1635639
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Xenopus tropicalis
Source
Yeast
Validations
N° du produit
ABIN1620787
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits Protein Phosphatase 4, Regulatory Subunit 2
: "PPP4R2 regulates neuronal cell differentiation and survival, functionally cooperating with SMN." dans: European journal of cell biology, Vol. 91, Issue 8, pp. 662-74, (2012) (PubMed).: "A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein." dans: Molecular & cellular proteomics : MCP, Vol. 8, Issue 1, pp. 157-71, (2009) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à Protein Phosphatase 4, Regulatory Subunit 2
protein phosphatase 4 regulatory subunit 2 (PPP4R2), protein phosphatase 4, regulatory subunit 2 (Ppp4r2), protein phosphatase 4, regulatory subunit 2a (ppp4r2a), protein phosphatase 4 regulatory subunit 2 S homeolog (ppp4r2.S), protein phosphatase 4 regulatory subunit 2 (ppp4r2), protein phosphatase 4 regulatory subunit 2 L homeolog (ppp4r2.L), protein phosphatase 4, regulatory subunit 2b (ppp4r2b), BE691708, C230060M08Rik, fe11b04, PP4R2, ppp4r2, ppp4r2-B, wu:fa17h08, wu:fc23g05, wu:fe11b04Protein level used designations for Protein Phosphatase 4, Regulatory Subunit 2
- serine/threonine-protein phosphatase 4 regulatory subunit 2
- serine/threonine-protein phosphatase 4 regulatory subunit 2-A
- protein phosphatase 4, regulatory subunit 2
- serine/threonine-protein phosphatase 4 regulatory subunit 2-B
- Serine/threonine-protein phosphatase 4 regulatory subunit 2
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