Protein tyrosine Phosphatase, Receptor Type, J Produits
(Protein tyrosine Phosphatase, Receptor Type, J (PTPRJ))
Catégories
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories Protein tyrosine Phosphatase, Receptor Type, J en vedette
Protein tyrosine Phosphatase, Receptor Type, J Anticorps
High quality antibodies with extensive validation data.
Protein tyrosine Phosphatase, Receptor Type, J Kits ELISA
Reliable ELISA kits for a wide range of species.
Protein tyrosine Phosphatase, Receptor Type, J Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Protein tyrosine Phosphatase, Receptor Type, J recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7441778
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
- (4)
N° du produit
ABIN7440614
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
N° du produit
ABIN7193256
Quantité
100 μL
Fiche technique
Fiche technique
Protein tyrosine Phosphatase, Receptor Type, J recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969755
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958961
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN4882596
Quantité
96 tests
Fiche technique
Fiche technique
Protein tyrosine Phosphatase, Receptor Type, J recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124686
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316873
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7412191
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Protein tyrosine Phosphatase, Receptor Type, J
: "A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis." dans: Oncotarget, Vol. 8, Issue 6, pp. 10091-10102, (2018) (PubMed).: "The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis." dans: Oncogene, Vol. 34, Issue 44, pp. 5536-47, (2015) (PubMed).
: "Phosphorylation of DEP-1/PTPRJ on threonine 1318 regulates Src activation and endothelial cell permeability induced by vascular endothelial growth factor." dans: Cellular signalling, Vol. 26, Issue 6, pp. 1283-93, (2014) (PubMed).
: "Polymorphisms of protein tyrosine phosphatase CD148 influence FcγRIIA-dependent platelet activation and the risk of heparin-induced thrombocytopenia." dans: Blood, Vol. 120, Issue 6, pp. 1309-16, (2012) (PubMed).
: "Systematic validation of specific phenotypic markers for in vitro polarized human macrophages." dans: Journal of immunological methods, Vol. 375, Issue 1-2, pp. 196-206, (2012) (PubMed).
: "Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148." dans: The Journal of biological chemistry, Vol. 286, Issue 25, pp. 22101-12, (2011) (PubMed).
: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." dans: Immunology letters, Vol. 134, Issue 2, pp. 113-21, (2010) (PubMed).
: "Analysis of HLDA9 mAbs on plasmacytoid dendritic cells." dans: Immunology letters, Vol. 134, Issue 2, pp. 167-73, (2010) (PubMed).
: "Tumor suppressor density-enhanced phosphatase-1 (DEP-1) inhibits the RAS pathway by direct dephosphorylation of ERK1/2 kinases." dans: The Journal of biological chemistry, Vol. 284, Issue 33, pp. 22048-58, (2009) (PubMed).
: "CD148 and CD27 are expressed in B cell lymphomas derived from both memory and naïve B cells." dans: Leukemia & lymphoma, Vol. 43, Issue 9, pp. 1855-8, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à Protein tyrosine Phosphatase, Receptor Type, J
acid phosphatase 1 (ACP1), protein tyrosine phosphatase, receptor type J (PTPRJ), protein tyrosine phosphatase, receptor type, J (Ptprj), protein tyrosine phosphatase, receptor type, J (PTPRJ), protein tyrosine phosphatase, receptor type, J (EUBREC_2762), AI450271, BET, Byp, CD148, DEP-1, DEP1, HAAP, HPTPeta, Ptpb2, PTPbeta2, PTPRJ, R-PTP-ETA, RPTPJ, Scc-1, SCC1, Scc1Protein level used designations for Protein tyrosine Phosphatase, Receptor Type, J
- LMW-PTP
- LMW-PTPase
- acid phosphatase of erythrocyte
- adipocyte acid phosphatase
- cytoplasmic phosphotyrosyl protein phosphatase
- low molecular weight cytosolic acid phosphatase
- low molecular weight phosphotyrosine protein phosphatase
- protein tyrosine phosphatase
- red cell acid phosphatase 1
- CD148 antigen
- DEP-1
- HPTP eta
- R-PTP-J
- density-enhanced phosphatase 1
- human density enhanced phosphatase-1
- protein tyrosine phosphatase, receptor type, J polypeptide
- protein-tyrosine phosphatase eta
- protein-tyrosine phosphatase receptor type J
- receptor-type tyrosine-protein phosphatase eta
- susceptibility to colon cancer 1, mouse, homolog of
- HPTP beta-like tyrosine phosphatase
- R-PTP-eta
- colon tumor susceptibility 1
- susceptibility to colon cancer 1
- density enhanced phosphatase-1
- supporting-cell antigen
- protein tyrosine phosphatase, receptor type, J
- receptor-type tyrosine-protein phosphatase eta-like
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