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Proteoglycan 4 Produits

(Proteoglycan 4 (PRG4))
The protein encoded by this gene is a large proteoglycan specifically synthesized by chondrocytes located at the surface of articular cartilage, and also by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories Proteoglycan 4 en vedette

Proteoglycan 4 Anticorps

High quality antibodies with extensive validation data.

Proteoglycan 4 Kits ELISA

Reliable ELISA kits for a wide range of species.

Proteoglycan 4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Proteoglycan 4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (4)
N° du produit ABIN7436231
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (2)
N° du produit ABIN6244267
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN523617
Quantité 100 μg
Fiche technique Fiche technique

Proteoglycan 4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6958971
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969764
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962372
Quantité 96 tests
Fiche technique Fiche technique

Proteoglycan 4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1316188
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7423159
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7398845
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Proteoglycan 4

Toledo, Golden, Campos, Cuello, Sorrentino, Lewis, Varki, Nizet, Smith, Esko: "Proteomic atlas of organ vasculopathies triggered by Staphylococcus aureus sepsis." dans: Nature communications, Vol. 10, Issue 1, pp. 4656, (2019) (PubMed).

Clearfield, Xin, Yadav, Rowe, Wei: "Osteochondral Differentiation of Fluorescent Multireporter Cells on Zonally-Organized Biomaterials." dans: Tissue engineering. Part A, (2018) (PubMed).

Ogawa, Matsumoto, Terabayashi, Kawashima, Takeuchi, Akiyama: "Association of lubricin concentration in synovial fluid and clinical status of osteoarthritic knee." dans: Modern rheumatology, Vol. 27, Issue 3, pp. 489-492, (2016) (PubMed).

Roffi, Filardo, Assirelli, Cavallo, Cenacchi, Facchini, Grigolo, Kon, Mariani, Pratelli, Pulsatelli, Marcacci: "Does platelet-rich plasma freeze-thawing influence growth factor release and their effects on chondrocytes and synoviocytes?" dans: BioMed research international, Vol. 2014, pp. 692913, (2014) (PubMed).

Guo, Fang, Li, Ke, Deng, Meng, Li, Long: "Up-regulation of proteoglycan 4 in temporomandibular osteoarthritic synovial cells by hyaluronic acid." dans: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, (2014) (PubMed).

Shepard, Jeong, Maihle, OBrien, Dealy: "Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo." dans: Arthritis research & therapy, Vol. 15, Issue 3, pp. R60, (2014) (PubMed).

Musumeci, Loreto, Carnazza, Cardile, Leonardi: "Acute injury affects lubricin expression in knee menisci: an immunohistochemical study." dans: Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, Vol. 195, Issue 2, pp. 151-8, (2013) (PubMed).

Liu, Tefft, Roberts, Zhang, Ren, Li, Huang, Zhang, Phillips, Wu: "Cardioprotective proteins upregulated in the liver in response to experimental myocardial ischemia." dans: American journal of physiology. Heart and circulatory physiology, Vol. 303, Issue 12, pp. H1446-58, (2012) (PubMed).

Leonardi, Musumeci, Sicurezza, Loreto: "Lubricin in human temporomandibular joint disc: an immunohistochemical study." dans: Archives of oral biology, Vol. 57, Issue 6, pp. 614-9, (2012) (PubMed).

Leonardi, Rusu, Loreto, Loreto, Musumeci: "Immunolocalization and expression of lubricin in the bilaminar zone of the human temporomandibular joint disc." dans: Acta histochemica, Vol. 114, Issue 1, pp. 1-5, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à Proteoglycan 4

proteoglycan 4 (PRG4), proteoglycan 4 (Prg4), proteoglycan 4b (prg4b), proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) (Prg4), bG174L6.2, CACP, DOL54, HAPO, JCAP, lubricin, MSF, prg4, PRG4, si:dkey-97o5.3, SZP, zgc:122988

Protein level used designations for Proteoglycan 4

  • articular superficial zone protein
  • bG174L6.2 (MSF: megakaryocyte stimulating factor )
  • lubricin
  • megakaryocyte stimulating factor
  • megakaryocyte-stimulating factor
  • superficial zone proteoglycan
  • MLL septin-like fusion
  • proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)
  • proteoglycan 4
  • p53-responsive gene 4
  • proteoglycan 3
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