ILK Protein (AA 1-452) (His tag)

N° du produit ABIN1000951

Détail du produit

Antigène: ILK (Integrin-Linked Kinase (ILK))

Type de proteíne: Recombinant

Attributs du protein: AA 1-452

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ILK protéine est marqué à la His tag.

Application: Western Blotting (WB), Control (Ct)

Fonction: Integrin-Linked Kinase (ILK) (Western Blot Control)

Séquence: MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW MIVPILEKMQ DK

Attributs du produit: recombinant ILK1 comprises a 452 amino acid fragment (1-452) corresponding to the mature ILK1 fulllength protein and is expressed in E. coli with an aminoterminal hexahistidine tag.

Pureté: > 95 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C

Détail du antigène

Antigène: ILK (Integrin-Linked Kinase (ILK))

Autre désignation: Integrin-Linked Kinase (ILK Produits)

Synonymes: CG10504 Protein, CT29478 Protein, DmILK Protein, Dmel\\CG10504 Protein, ILK Protein, ilk Protein, l(3)78Ca Protein, p59 Protein, AA511515 Protein, ESTM24 Protein, zgc:65842 Protein, ILK-1 Protein, ILK-2 Protein, P59 Protein, p59ILK Protein, Integrin linked kinase Protein, integrin linked kinase Protein, integrin linked kinase S homeolog Protein, integrin-linked protein kinase Protein, integrin-linked kinase Protein, Ilk Protein, ILK Protein, ilk.S Protein, CpipJ_CPIJ016644 Protein, Bm1_20815 Protein, Tsp_07213 Protein, Tsp_07224 Protein, Tsp_15354 Protein, ilk Protein

Sujet: Integrin-linked kinase (ILK1) is a serine/threonine protein kinase, containing 4 ankyrin-like repeats. ILK1 interacts with the cytoplasmic domains of integrin β1 and β3 subunits as well as several adaptors and signalling proteins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. ILK1 has been reported to regulate a number of biological properties including anchorage-independent cell cycle progression, tumour cell invasion and apoptosis. Over-expression of ILK1 has been documented in a wide variety of human malignancies.,ILK-1, ILK-2, 59 kDa serine/threonine-protein kinase, p59, p59ILK.

Poids moléculaire: 55.92 kDa

UniProt: Q13418

Pathways: Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration