IL-6 Receptor Protein (AA 20-357) (His tag)

N° du produit ABIN1001031

Détail du produit

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Type de proteíne: Recombinant

Attributs du protein: AA 20-357

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette IL-6 Receptor protéine est marqué à la His tag.

Application: Western Blotting (WB), Control (Ct)

Fonction: Interleukin-6 Soluable Receptor (IL-6SR) (Western Blot Control)

Séquence: LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH DDNILFRDSA NATSLPVQ

Attributs du produit: recombinant IL6-sR comprises a 338 amino acid fragment (20-357) corresponding to the mature IL6- sR protein and is expressed in E. coli with an aminoterminal hexahistidine tag.

Pureté: > 95 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C

Détail du antigène

Antigène: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Autre désignation: Interleukin-6 Soluable Receptor (IL6R Produits)

Synonymes: IL6R Protein, il-6ra Protein, CD126 Protein, IL-6R-1 Protein, IL-6RA Protein, IL6Q Protein, IL6RA Protein, IL6RQ Protein, gp80 Protein, IL6R1 Protein, Il6ra Protein, IL-6Ralpha Protein, IL-6R Protein, Il6r Protein, interleukin 6 receptor Protein, interleukin 6 receptor, alpha Protein, IL6R Protein, il6r Protein, Il6r Protein, Il6ra Protein

Sujet: The IL-6 receptor complex is composed of two membrane glycoproteins: the low affinity receptor and the signaltransducing component. The soluble form of IL6R is found in the urine of healthy adult humans and the serum of HIV positive individuals, as well as in the cell culture supernatants of stimulated PBMC's. This soluble form of IL6R results from either proteolytic cleavage from the membrane, or an isoform derived splice variant.,IL6R-alpha, IL-6R 1, CD126 antigen, IL6RA, interleukin 6 receptor, interleukin 6 receptor alpha subunit, Interleukin6 receptor alpha chain precursor.

Poids moléculaire: 42.45 kDa

UniProt: P08887

Pathways: Signalistation JAK/STAT, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints