recombinant TIMP-1 comprises a 184 amino acid fragment (24-207) corresponding to the mature TIMP1 protein and is expressed in E. coli with an aminoterminal hexahistidine tag.
TIMP1
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS, WB, Imm, PC
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Buffer
Supplied in 1x Laemmli Buffer (25 mM Tris-HCl pH 6.8, 50 mM DTT, 1 % (w/v) SDS, 0.1 % (w/v) Bromophenol Blue, 2.5 % Glycerol).
Agent conservateur
Dithiothreitol (DTT)
Précaution d'utilisation
This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20 °C
Antigène
TIMP1
(TIMP Metallopeptidase Inhibitor 1 (TIMP1))
Autre désignation
Tissue Inhibitor of Metalloproteinase 1 (TIMP1 Produits)
Synonymes
TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein
Sujet
TIMP-1 is an inducible glycoprotein, which is synthesized by many different cell types. TIMP-1 binds in a reversible fashion to matrix metalloproteinases, with regions in the Nterminal domain binding to the MMP substrate-binding site. TIMP-1 also functions as erthyroid-potentiating activity via translocation to the nucleus and also in inhibiting apoptosis in B-cells.,Soluble tumour necrosis factor receptor-1, Tumour necrosis factor receptor subfamily member 1A (TNFRSF1A), Tumour necrosis factor binding protein I (TNFBPI), Tumour necrosis factor receptor type I (TNFRI), Tumour necrosis factor-alpha receptor (TNFAR), CD120a antigen, p55, p55-R, p60, MGC19588.