CD8B Protein (AA 22-170) (His tag)
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- Antigène Voir toutes CD8B Protéines
- CD8B (CD8b Molecule (CD8B))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 22-170
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette CD8B protéine est marqué à la His tag.
- Fonction
- Recombinant Human CD8 β Chain/CD8B (C-6His)
- Séquence
- LQQTPAYIKV QTNKMVMLSC EAKISLSNMR IYWLRQRQAP SSDSHHEFLA LWDSAKGTIH GEEVEQEKIA VFRDASRFIL NLTSVKPEDS GIYFCMIVGS PELTFGKGTQ LSVVDFLPTT AQPTKKSTLK KRVCRLPRPE TQKGPLCSPV DHHHHHH
- Attributs du produit
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Recombinant Human CD8 β Chain/CD8B (C-6His)
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CD8B Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Stock
- 4 °C/-20 °C/-80 °C
- Stockage commentaire
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- CD8B (CD8b Molecule (CD8B))
- Autre désignation
- T-Cell Surface Glycoprotein CD8beta Chain/CD8B (CD8B Produits)
- Synonymes
- Cd8b Protein, Ly-3 Protein, Ly-C Protein, Lyt-3 Protein, CD8B1 Protein, LEU2 Protein, LY3 Protein, LYT3 Protein, P37 Protein, Cd8b1 Protein, CD8b molecule Protein, CD8 antigen, beta chain 1 Protein, Cd8b Protein, CD8B Protein, Cd8b1 Protein
- Sujet
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Recombinant Human T-Cell Surface Glycoprotein CD8β Chain/CD8B is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Leu22-Pro170) of Human CD8B fused with a polyhistidine tag at the C-terminus.
T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two α chains, or a heterodimer composed of one α and one β chain. Both α and β chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. - Poids moléculaire
- 17.8 kDa
- UniProt
- P10966
- Pathways
- TCR Signaling
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