CRNN Protein (AA 1-140) (His tag)

N° du produit ABIN1096431

Détail du produit

Antigène: CRNN (Cornulin (CRNN))

Type de proteíne: Recombinant

Attributs du protein: AA 1-140

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CRNN protéine est marqué à la His tag.

Fonction: Recombinant Human Cornulin (N-6His)

Séquence: MGSSHHHHHH SSGLVPRGSH MPQLLQNING IIEAFRRYAR TEGNCTALTR GELKRLLEQE FADVIVKPHD PATVDEVLRL LDEDHTGTVE FKEFLVLVFK VAQACFKTLS ESAEGACGSQ ESGSLHSGAS QELGEGQRSG TEVGRAGKGQ HYEGSSHRQS

Attributs du produit: Recombinant Human Cornulin is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser140) of Human Cornulin fused with a His tag at the N-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: CRNN (Cornulin (CRNN))

Autre désignation: cornulin (CRNN Produits)

Synonymes: C1orf10 Protein, DRC1 Protein, PDRC1 Protein, SEP53 Protein, RGD1311778 Protein, Gm1015 Protein, cornulin Protein, CRNN Protein, Crnn Protein, LOC100359146 Protein

Sub Type: Fusionprotein

Sujet: Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When Cornulin is overexpressed in oral squamous carcinoma cell lines, it regulates negatively cell proliferation by the induction of G1 arrest.
Alternative Names: Cornulin, 53 kDa Putative Calcium-Binding Protein, 53 kDa Squamous Epithelial-Induced Stress Protein, 58 kDa Heat Shock Protein, Squamous Epithelial Heat Shock Protein 53, Tumor-Related Protein, CRNN, C1orf10, DRC1, PDRC1, SEP53

Poids moléculaire: 17.45 kDa

UniProt: Q9UBG3