ITPA Protein (AA 1-194) (His tag)
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- Antigène Voir toutes ITPA Protéines
- ITPA (Inosine Triphosphatase (ITPA))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-194
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette ITPA protéine est marqué à la His tag.
- Fonction
- Recombinant Human Inosine Triphosphate Pyrophosphatase/ITPase (C-6His)
- Séquence
- MAASLVGKKI VFVTGNAKKL EEVVQILGDK FPCTLVAQKI DLPEYQGEPD EISIQKCQEA VRQVQGPVLV EDTCLCFNAL GGLPGPYIKW FLEKLKPEGL HQLLAGFEDK SAYALCTFAL STGDPSQPVR LFRGRTSGRI VAPRGCQDFG WDPCFQPDGY EQTYAEMPKA EKNAVSHRFR ALLELQEYFG SLAALEHHHH HH
- Attributs du produit
- Recombinant Human Inosine Triphosphate Pyrophosphatase/ITPase is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Ala194) of Human ITPA fused with a 6His tag at the C-terminus.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ITPA Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.
- Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Stock
- -80 °C
- Stockage commentaire
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Date de péremption
- 6 months
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- Antigène
- ITPA (Inosine Triphosphatase (ITPA))
- Autre désignation
- ITPA (ITPA Produits)
- Synonymes
- DDBDRAFT_0215619 Protein, DDBDRAFT_0238062 Protein, DDB_0215619 Protein, DDB_0238062 Protein, 2010016I08Rik Protein, AU020102 Protein, Itp Protein, C20orf37 Protein, HLC14-06-P Protein, dJ794I6.3 Protein, ITPase Protein, NTPase Protein, si:ch73-18j6.1 Protein, si:dkey-19f21.1 Protein, inosine triphosphatase Protein, inosine triphosphatase (nucleoside triphosphate pyrophosphatase) Protein, Inosine triphosphate pyrophosphatase Protein, inosine triphosphatase S homeolog Protein, itpa Protein, ITPA Protein, LOC733043 Protein, Itpa Protein, pco148511 Protein, itpa.S Protein
- Sub Type
- Fusionprotein
- Sujet
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Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) to the monophosphate nucleotide (IMP) and diphosphate. The ITPase enzyme acts as a homodimer and does not distinguish between the deoxy- and ribose forms. ITPase probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Defects in ITPase is thought to be inherited and is characterized by an over-accumulation of ITP in erythocytes, leukocytes and fibroblasts.
Alternative Names: Inosine Triphosphate Pyrophosphatase, ITPase, Inosine Triphosphatase, Non-Canonical Purine NTP Pyrophosphatase, Non-Standard Purine NTP Pyrophosphatase, Nucleoside-Triphosphate Diphosphatase, Nucleoside-Triphosphate Pyrophosphatase, NTPase, Putative Oncog - Poids moléculaire
- 22.5 kDa
- UniProt
- Q9BY32
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