MOG Protein (AA 30-154)

N° du produit ABIN1097170

Détail du produit

Antigène: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: AA 30-154

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func)

Fonction: Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG

Séquence: MGQFRVIGPR HPIRALVGDE VELPCRISPG KNATGMEVGW YRPPFSRVVH LYRNGKDQDG DQAPEYRGRT ELLKDAIGEG KVTLRIRNVR FSDEGGFTCF FRDHSYQEEA AMELKVEDPF YWVSPGHHHH HH

Attributs du produit: Recombinant Human Myelin Oligodendrocyte Glycoprotein/MOG is produced with our E. coli expression system. The target protein is expressed with sequence (Gly30-Gly154) of Human MOG protein.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Commentaires:

Biological activity: Tested for capability to induce EAE in rodents and monkeys

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.5.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 3 months

Détail du antigène

Antigène: MOG (Myelin Oligodendrocyte Glycoprotein (MOG))

Autre désignation: mog-protein (MOG Produits)

Synonymes: MOGIG2 Protein, NRCLP7 Protein, B230317G11Rik Protein, MOG Protein, myelin oligodendrocyte glycoprotein Protein, MOG Protein, Mog Protein

Sujet: Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.
Alternative Names: Myelin-Oligodendrocyte Glycoprotein, MOG

Poids moléculaire: 15.2 kDa

UniProt: Q16653