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Nerve Growth Factor Protein (NGF) (AA 19-241)

NGF Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN1097406
  • Antigène Voir toutes Nerve Growth Factor (NGF) Protéines
    Nerve Growth Factor (NGF)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 19-241
    Origine
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 23
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Fonction
    Recombinant Human pro-Nerve Growth Factor/pro-NGF (Glu19-Ala241)
    Séquence
    MEPHSESNVP AGHTIPQAHW TKLQHSLDTA LRRARSAPAA AIAARVAGQT RNITVDPRLF KKRRLRSPRV LFSTQPPREA ADTQDLDFEV GGAAPFNRTH RSKRSSSHPI FHRGEFSVCD SVSVWVGDKT TATDIKGKEV MVLGEVNINN SVFKQYFFET KCRDPNPVDS GCRGIDSKHW NSYCTTTHTF VKALTMDGKQ AAWRFIRIDT ACVCVLSRKA VRRA
    Attributs du produit
    Recombinant Human precursor form of Nerve Growth Factor/pro-NGF produced in E. coli is a non-glycosylated non-covalently linked homodimer with each polypeptide chain containing 222 amino acids with an extra N-terminal Met with a molecular mass of 25kDa.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product NGF Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.2.
    Conseil sur la manipulation
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Stock
    4 °C/-20 °C/-80 °C
    Stockage commentaire
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    3 months
  • Antigène
    Nerve Growth Factor (NGF)
    Abstract
    NGF Produits
    Synonymes
    Beta-NGF Protein, HSAN5 Protein, NGFB Protein, Ngfb Protein, ngfb Protein, ns:zft386 Protein, xx:zft386 Protein, zgc:109730 Protein, beta-NGF Protein, hsan5 Protein, beta-ngf Protein, NGF Protein, ngf Protein, nerve growth factor Protein, nerve growth factor b (beta polypeptide) Protein, nerve growth factor S homeolog Protein, NGF Protein, Ngf Protein, ngfb Protein, ngf Protein, ngf.S Protein
    Sujet
    The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
    Alternative Names: Beta-Nerve Growth Factor, Beta-NGF, NGF, NGFB
    Poids moléculaire
    25 kDa
    UniProt
    P01138
    Pathways
    Regulation of Cell Size
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