MVK Protein (His tag)

N° du produit ABIN1098525

Détail du produit

Antigène: MVK (Mevalonate Kinase (MVK))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MVK protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Purification: purified by chromatography

Pureté: > 90 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Mevalonate kinase, LRBP, MK, MVLK

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol, 1 MM DTT

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: MVK (Mevalonate Kinase (MVK))

Autre désignation: MVK (MVK Produits)

Synonymes: F21A20.160 Protein, F21A20_160 Protein, MEVALONATE KINASE Protein, MVK Protein, mevalonate kinase Protein, DDBDRAFT_0168621 Protein, DDBDRAFT_0302479 Protein, DDB_0168621 Protein, DDB_0302479 Protein, LRBP Protein, MK Protein, MVLK Protein, POROK3 Protein, 2310010A05Rik Protein, AI256848 Protein, AI414037 Protein, zgc:103473 Protein, mevalonate kinase Protein, mvk Protein, hypothetical protein Protein, MVK Protein, MK Protein, MA_RS03165 Protein, PAB_RS02890 Protein, LMOf2365_0011 Protein, mvk Protein, RCI_RS14145 Protein, TGAM_RS08735 Protein, MMAH_RS07705 Protein, TAGG_RS01605 Protein, SHELL_RS02965 Protein, MVOL_RS03085 Protein, Igag_1464 Protein, VDIS_RS11260 Protein, MFER_RS04560 Protein, DESMU_RS01555 Protein, ARCVE_RS02955 Protein, MZHIL_RS05110 Protein, Mvk Protein

Sujet: Mevalonate kinase, also known as MVK, belongs to the GHMP kinase family. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive,hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Recombinant human MVK protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Poids moléculaire: 44.8 kDa (419aa) confirmed by MALDI-TOF

NCBI Accession: NP_001107657