EYA2 Protein (His tag)
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- Antigène Voir toutes EYA2 Protéines
- EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette EYA2 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by using conventional chromatography.
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product EYA2 Protéine
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- Commentaires
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Synonyms: Eyes absent homolog 2, EAB1, MGC10614
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 40% glycerol, 0.15 M NaCl, 1 MM DTT
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
- Autre désignation
- EYA2 (EYA2 Produits)
- Synonymes
- EYA2 Protein, zgc:92279 Protein, eab1 Protein, Eab1 Protein, EAB1 Protein, EYA transcriptional coactivator and phosphatase 2 Protein, EYA2 Protein, eya2 Protein, Eya2 Protein
- Sujet
- EYA2, also known as eyes absent homolog 2, is a member of tyrosine phosphatase family that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). This protein promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. Recombinant human EYA2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- Poids moléculaire
- 33.2 kDa (295aa), confirmed by MALDI-TOF
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