HFE Protein (His tag)
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- Antigène Voir toutes HFE Protéines
- HFE (Hemochromatosis (HFE))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette HFE protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Pureté
- > 85 % by SDS - PAGE
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Hemochromatosis (HFE) (AA 115-205) protein (GST tag)
HFE Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA
Hemochromatosis (HFE) proteinHFE Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 85 % pure SDS
Hemochromatosis (HFE) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)HFE Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Hemochromatosis (HFE) (Transcript Variant 6) protein (Myc-DYKDDDDK Tag)HFE Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Hemochromatosis (HFE) (Transcript Variant 9) protein (Myc-DYKDDDDK Tag)HFE Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Commentaires
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Synonyms: Hereditary hemochromatosis protein, HFE1, HH, HLA-H, MVCD7, TFQTL2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea, 10% glycerol
- Stock
- 4 °C
- Stockage commentaire
- Avoid repeated freezing and thawing cycles.
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- Antigène
- HFE (Hemochromatosis (HFE))
- Autre désignation
- HFE (HFE Produits)
- Synonymes
- HFE1 Protein, HH Protein, HLA-H Protein, MVCD7 Protein, TFQTL2 Protein, MR2 Protein, hemochromatosis Protein, HFE Protein, Hfe Protein
- Sujet
- HFE, also known as HLA-H, belongs to the MHC class I family. This protein contains 1 Ig-like C1-type (immunoglobulin-like) domain. HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor (TFR) with transferrin. It binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. Recombinant human HFE protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Poids moléculaire
- 35.7kDa (308aa)
- NCBI Accession
- NP_000401
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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