IGLL1 Protein (His tag)

N° du produit ABIN1098784

Détail du produit

Antigène: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette IGLL1 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Pureté: > 85 % by SDS - PAGE

Information d'application

Commentaires:

Synonyms: Immunoglobulin lambda-like polypeptide 1, 14.1, AGM2, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M urea, 10% glycerol

Stock: 4 °C

Stockage commentaire: Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Autre désignation: IGLL1 (IGLL1 Produits)

Synonymes: 14.1 Protein, AGM2 Protein, CD179b Protein, IGL1 Protein, IGL5 Protein, IGLJ14.1 Protein, IGLL Protein, IGO Protein, IGVPB Protein, VPREB2 Protein, IGLV Protein, IGLL1 Protein, MGC151892 Protein, Igll1 Protein, BB139905 Protein, Igl-5 Protein, Igll Protein, Lambda5 Protein, immunoglobulin lambda like polypeptide 1 Protein, immunoglobulin lambda-like polypeptide 1 Protein, IGLL1 Protein, Igll1 Protein

Sujet: The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human IGLL1protein, fused to His-tag at N-terminus, was expressed in E.coli.

Poids moléculaire: 21.5 kDa (199aa)

NCBI Accession: NP_064455

Pathways: Regulation of Cell Size