IL-33 Protein (AA 109-266)
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- Antigène Voir toutes IL-33 (IL33) Protéines
- IL-33 (IL33) (Interleukin 33 (IL33))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 109-266
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Origine
- Humain, Souris
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Specificité
- Binds to mouse and human ST2.
- Réactivité croisée
- Humain, Souris
- Attributs du produit
- Mouse IL-33 (aa 109-266) is untagged.
- Pureté
- >95 % (SDS-PAGE)
- niveau d'endotoxine
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product IL33 Protéine
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Interleukin 33 (IL33) (AA 112-270) protein
IL33 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 33 (IL33) (AA 109-270) (Active) protein (His tag)IL33 Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Interleukin 33 (IL33) (AA 109-270) protein (His tag)IL33 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Interleukin 33 (IL33) (AA 109-264) protein (His tag)IL33 Origine: Rat Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 33 (IL33) (AA 1-270) protein (GST tag)IL33 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 33 (IL33) (AA 171-269) protein (GST tag)IL33 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 33 (IL33) protein (His tag)IL33 Origine: Macaque rhésus Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Interleukin 33 (IL33) (AA 109-270) (Active) protein (His tag)IL33 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Activates ST2-dependent NF-kappaB pathway.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Date de péremption
- 6 months
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- Antigène
- IL-33 (IL33) (Interleukin 33 (IL33))
- Autre désignation
- IL-33 (IL33 Produits)
- Synonymes
- IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
- Sujet
- Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
- Poids moléculaire
- ~18kDa
- UniProt
- Q2YEJ4
- Pathways
- Production of Molecular Mediator of Immune Response
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