TNFRSF11A Protein (AA 31-214) (Fc Tag)
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- Antigène Voir toutes TNFRSF11A Protéines
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 31-214
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Origine
- Humain, Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette TNFRSF11A protéine est marqué à la Fc Tag.
- Application
- SDS-PAGE (SDS)
- Specificité
- Binds to mouse and human RANKL.
- Réactivité croisée
- Humain, Souris
- Attributs du produit
- Mouse RANK (aa 31-214) is fused at the C-terminus to the Fc portion of human IgG1.
- Pureté
- >95 % (SDS-PAGE)
- niveau d'endotoxine
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFRSF11A Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Inhibits mouse and human RANKL biological functions.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Date de péremption
- 6 months
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- Antigène
- TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))
- Autre désignation
- RANK (TNFRSF11A Produits)
- Synonymes
- RANK Protein, RGD1563614 Protein, TNFRSF11A Protein, Ly109 Protein, ODFR Protein, OFE Protein, Rank Protein, TRANCE-R Protein, mRANK Protein, CD265 Protein, FEO Protein, LOH18CR1 Protein, OPTB7 Protein, OSTS Protein, PDB2 Protein, TRANCER Protein, TNF receptor superfamily member 11A Protein, TNF receptor superfamily member 11a Protein, tumor necrosis factor receptor superfamily, member 11a, NFKB activator Protein, Tnfrsf11a Protein, TNFRSF11A Protein
- Sujet
- RANK (TRANCE-R, CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.
- Poids moléculaire
- ~55kDa (SDS-PAGE)
- UniProt
- O35305
- Pathways
- Signalisation NF-kappaB
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