CD200 Protein (CD200) (C-Term, Extracellular Domain)
-
- Antigène Voir toutes CD200 Protéines
- CD200
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- C-Term, Extracellular Domain
-
Origine
- Souris
-
Source
- HEK-293T Cells
- Specificité
- Optimized DNA sequence encoding extracellular domain of Mouse CD200 including a C-terminal 6His tag was expressed in HEK293 cells.
- Attributs du produit
- Recombinant Mouse CD200 is a monomer protein consisting of13 amino acid residue subunits, due to glycosylation migrates as an approximately 40-45kDa protein on SDS-PAGE.
- Pureté
- > 98 %, as determined by SDS-PAGE and HPLC
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
- Top Product
- Discover our top product CD200 Protéine
-
-
- Commentaires
-
The activity was tested by the ability of immobilized recombinant mouse CD200 (1 µg/mL,100 µL/well) to bind mouse CD200R1 with a linear range of 1-200 ng/mL
- Restrictions
- For Research Use only
-
- Buffer
- PBS solution, pH7.2
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- The lyophilized antibody is stable for at least 1 year from date of receipt at -20 °C. Upon reconstitution, this antibody can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months without detectable loss of activity.
- Date de péremption
- 12 months
-
- Antigène
- CD200
- Autre désignation
- CD200 (CD200 Produits)
- Synonymes
- MOX1 Protein, MOX2 Protein, MRC Protein, OX-2 Protein, CD200 Protein, Cspmo2 Protein, MRCOX2 Protein, Mox2 Protein, DKFZp459C0716 Protein, OX2 Protein, CD200 molecule Protein, Cd200 molecule Protein, CD200 antigen Protein, CD200 Protein, Cd200 Protein
- Sujet
- CD7 is a 40-kD member of the Ig gene superfamily that is expressed on a major subset of human peripheral T lymphocytes and NK cells. CD7 can complex with CD3 and CD45 molecules, and CD7 signaling involves both protein kinase C and protein tyrosine kinase. CD7 has been shown to be a functional signal-transducing molecule on resting NK cells. Although the function of CD7 is unknown, studies suggest that CD7 may be involved in T and NK cell activation and/or adhesion. In TCRbeta T cells, cross-linking of CD7 leads to rapid increases in intracellular calcium concentrations, induces CD7 cytoplasmic domain association with phosphotidylinositol-3-kinase, synergizes with submitogenic amounts of CD3 mAbs to induce T cell activation, modulates T cell adhesion, and increases T cell IL-2 production and IL-2 receptor expression. In TCR T cells, cross-linking of CD7 leads to cell activation and induction of TNF-a, TNF-b, and granulocyte-macrophage CSF mRNA.
- UniProt
- O54901
-