IL10RB Protein (C-Term, Extracellular Domain)

N° du produit ABIN1684696

Détail du produit

Antigène: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Type de proteíne: Recombinant

Attributs du protein: C-Term, Extracellular Domain

Origine: Souris

Source: HEK-293 Cells

Séquence: MAPCVAGWLG GFLLVPALGM IPPPEKVRMN SVNFKNILQW EVPAFPKTNL TFTAQYESYR SFQDHCKRTA STQCDFSHLS KYGDYTVRVR AELADEHSEW VNVTFCPVED TIIGPPEMQI 130140150160170180ESLAESLHLR FSAPQIENEP ETWTLKNIYD SWAYRVQYWK NGTNEKFQVV SPYDSEVLRN 1900010203040LEPWTTYCIQ VQGFLLDQNR TGEWSEPICE RTGNDEITPS WIVAIILIVS VLVVFLFLLG 5060708090300CFVVLWLIYK KTKHTFRSGT SLPQHLKEFL GHPHHSTFLL FSFPPPEEAE VFDKLSIISE 310320330340ESEGSKQSPE DNCASEPPSD PGPRELESKD EAPSPPHDDP KLLTSTSEV

Specificité: DNA sequence encoding extracellular domain of Mouse IL-10RB fused to a C-terminal polyHis tag was expressed in HEK cells.

Attributs du produit: Recombinant Mouse Interleukin-10RB is a monomer consisting of12 amino acid residue subunits, and migrates as an approximately 46 kDa protein under reducing conditions in SDS-PAGE.

Pureté: > 90 %, as determined by SDS-PAGE and HPLC

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Buffer: PBS solution pH 7.4.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

Date de péremption: 12-24 months

Détail du antigène

Antigène: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Autre désignation: IL10RB (IL10RB Produits)

Synonymes: IL10R2 Protein, IL10RB Protein, il10r2 Protein, CDW210B Protein, CRF2-4 Protein, CRFB4 Protein, D21S58 Protein, D21S66 Protein, IL-10R2 Protein, 6620401D04Rik Protein, AI528744 Protein, Crfb4 Protein, D16H21S58 Protein, D21S58h Protein, Il10r2 Protein, RGD1560373 Protein, interleukin 10 receptor subunit beta Protein, interleukin 10 receptor subunit beta S homeolog Protein, interleukin-10 receptor subunit beta Protein, interleukin 10 receptor, beta Protein, IL10RB Protein, il10rb.S Protein, LOC473966 Protein, LOC478404 Protein, il10rb Protein, Il10rb Protein

Sujet: TNF-beta TNF-beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-beta is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-alpha TNF-beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-beta which effectively anchors the TNF-beta to the cell surface. TNF-beta is cytotoxic to a wide range of tumor cells.

UniProt: Q61190