PTGDS Protein (AA 23-190) (His tag)
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- Antigène Voir toutes PTGDS Protéines
- PTGDS (Prostaglandin D2 Synthase (PTGDS))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 23-190
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Origine
- Humain
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Source
- Human Cells
- Purification/Conjugué
- Cette PTGDS protéine est marqué à la His tag.
- Fonction
- Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS (C-6His)
- Séquence
- APEAQVSVQP NFQQDKFLGR WFSAGLASNS SWLREKKAAL SMCKSVVAPA TDGGLNLTST FLRKNQCETR TMLLQPAGSL GSYSYRSPHW GSTYSVSVVE TDYDQYALLY SQGSKGPGED FRMATLYSRT QTPRAELKEK FTAFCKAQGF TEDTIVFLPQ TDKCMTEQVD HHHHHH
- Attributs du produit
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Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS (C-6His)
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Stérilité
- 0.2 μm filtered
- niveau d'endotoxine
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PTGDS Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,10 % Glycerol, pH 7.5.
- Conseil sur la manipulation
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Stock
- -80 °C
- Stockage commentaire
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Date de péremption
- 6 months
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- Antigène
- PTGDS (Prostaglandin D2 Synthase (PTGDS))
- Autre désignation
- Prostaglandin-H2 D-Isomerase/PTGDS (PTGDS Produits)
- Synonymes
- 6PGD Protein, GSTS Protein, GSTS1-1 Protein, PGD2 Protein, PGDS Protein, L-PGDS Protein, LPGDS Protein, PDS Protein, PGDS2 Protein, H-PGDS Protein, Ptgds2 Protein, 21kDa Protein, Ptgs3 Protein, PH2DISO Protein, phosphogluconate dehydrogenase Protein, hematopoietic prostaglandin D synthase Protein, prostaglandin D2 synthase Protein, prostaglandin D2 synthase (brain) Protein, prostaglandin D synthase Protein, prostaglandin D2 synthase 21kDa (brain) Protein, PGD Protein, HPGDS Protein, PTGDS Protein, Hpgds Protein, Ptgds Protein, LOC100009453 Protein
- Sujet
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Recombinant Human Prostaglandin-H2 D-Isomerase/PTGDS is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala23-Gln190) of Human PTGDS fused with a polyhistidine tag at the C-terminus.
Prostaglandin-H2 D-Isomerase (PTGDS) belongs to the Lipocalin family of calycin superfamily. PTGDS is preferentially expressed in the brain. PTGDS catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. PTGDS is involved in a variety of CNS functions, such as sedation, REM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. PTGDS binds small non-substrate lipophilic molecules and may act as a scavenger for harmful hydrophopic molecules and a secretory retinoid and thyroid hormone transporter. It possibly participates in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor, blood-testis barrier, the central nervous system and male reproductive system. - Poids moléculaire
- 19.7 kDa
- UniProt
- P41222
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