IL-7 Protein (AA 26-177) (His tag)

N° du produit ABIN1691666

Détail du produit

Antigène: IL-7 (IL7) (Interleukin 7 (IL7))

Type de proteíne: Recombinant

Attributs du protein: AA 26-177

Origine: Humain

Source: Human Cells

Purification/Conjugué: Cette IL-7 protéine est marqué à la His tag.

Fonction: Recombinant Human Interleukin-7/IL-7 (C-6His)

Séquence: DCDIEGKDGK QYESVLMVSI DQLLDSMKEI GSNCLNNEFN FFKRHICDAN KEGMFLFRAA RKLRQFLKMN STGDFDLHLL KVSEGTTILL NCTGQVKGRK PAALGEAQPT KSLEENKSLK EQKKLNDLCF LKRLLQEIKT CWNKILMGTK EHVDHHHHHH

Attributs du produit:

Recombinant Human Interleukin-7/IL-7 (C-6His)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: IL-7 (IL7) (Interleukin 7 (IL7))

Autre désignation: Interleukin-7/IL-7 (IL7 Produits)

Synonymes: IL7 Protein, IL-7 Protein, A630026I06Rik Protein, Il-7 Protein, hlb368 Protein, interleukin 7 Protein, IL7 Protein, Il7 Protein

Sujet: Recombinant Human Interleukin-7/IL-7 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asp26-His177) of Human IL-7 fused with a polyhistidine tag at the C-terminus.
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 AA precursor protein containing a 25 AA signal peptide and a 152 AA mature protein. Human and mouse IL7 share 65 % sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R γ for signal transduction.

Poids moléculaire: 18.4 kDa

UniProt: P13232

Pathways: Signalistation JAK/STAT