Recombinant Human Calcium/Calmodulin-Dependent Protein Kinase Type II Subunit Beta/CAMK2B is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Gln503) of Human CAMK2B fused with a 6His tag at the C-terminus.
Pureté
> 95 % as determined by reducing SDS-PAGE.
Stérilité
0.2 μm filtered
niveau d'endotoxine
Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
CAMK2B
Origine: Humain
Hôte: Tobacco (Nicotiana tabacum)
Recombinant
> 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, ELISA, SDS
CAMK2B
Origine: Souris
Hôte: Tobacco (Nicotiana tabacum)
Recombinant
> 80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, ELISA, SDS
CAMK2B
Origine: Rat
Hôte: Levure
Recombinant
> 90 %
ELISA
Restrictions
For Research Use only
Format
Liquid
Reconstitution
It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Buffer
Supplied as a 0.2 μm filtered solution of 10 mM HEPES, 150 mM NaCl, pH 7.5.
Conseil sur la manipulation
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
Stock
-80 °C
Stockage commentaire
Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Date de péremption
6 months
Antigène
CAMK2B
(Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
CAM2 Protein, CAMK2 Protein, CAMKB Protein, Camk2d Protein, Ck2b Protein, camk2 Protein, camk2b Protein, cam2 Protein, camkb Protein, CAMK2B Protein, calcium/calmodulin dependent protein kinase II beta Protein, calcium/calmodulin-dependent protein kinase II, beta Protein, calcium/calmodulin-dependent protein kinase II beta Protein, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog Protein, calcium/calmodulin dependent protein kinase (CaM kinase) II beta L homeolog Protein, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta Protein, CAMK2B Protein, Camk2b Protein, camk2a.S Protein, camk2b.L Protein
Sub Type
Fusionprotein
Sujet
Calcium/Calmodulin-Dependent Protein Kinase Type II Subunit Beta (CAMK2B) is a cytoplasmic protein that belongs to the serine/threonine protein kinase family and the Ca(2+)/calmodulin-dependent protein kinase subfamily. CAMK2B is a calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplamic reticulum Ca2+ transport in skeletal muscle. In neurons, CAMK2B plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. Alternative Names: Calcium/Calmodulin-Dependent Protein Kinase Type II Subunit Beta, CaM Kinase II Subunit Beta, CaMK-II Subunit Beta, CAMK2B, CAM2, CAMK2, CAMKB