CTH Protein (AA 1-405)

N° du produit ABIN1692129

Détail du produit

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Type de proteíne: Recombinant

Attributs du protein: AA 1-405

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human Cystathionine γ-Lyase/CTH

Séquence: GHMQEKDASS QGFLPHFQHF ATQAIHVGQD PEQWTSRAVV PPISLSTTFK QGAPGQHSGF EYSRSGNPTR NCLEKAVAAL DGAKYCLAFA SGLAATVTIT HLLKAGDQII CMDDVYGGTN RYFRQVASEF GLKISFVDCS KIKLLEAAIT PETKLVWIET PTNPTQKVID IEGCAHIVHK HGDIILVVDN TFMSPYFQRP LALGADISMY SATKYMNGHS DVVMGLVSVN CESLHNRLRF LQNSLGAVPS PIDCYLCNRG LKTLHVRMEK HFKNGMAVAQ FLESNPWVEK VIYPGLPSHP QHELVKRQCT GCTGMVTFYI KGTLQHAEIF LKNLKLFTLA ESLGGFESLA ELPAIMTHAS VLKNDRDVLG ISDTLIRLSV GLEDEEDLLE DLDQALKAAH PPSGSHS

Attributs du produit:

Recombinant Human Cystathionine γ-Lyase/CTH

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,20 % Glycerol, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: -80 °C

Stockage commentaire: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Autre désignation: Cystathionine gamma-Lyase/CTH (CTH Produits)

Synonymes: DYT17 Protein, DYT18 Protein, DYT9 Protein, EIG12 Protein, GLUT Protein, GLUT1 Protein, GLUT1DS Protein, HTLVR Protein, PED Protein, wu:fb48e03 Protein, wu:fb58d08 Protein, zgc:66001 Protein, zgc:85785 Protein, CTH Protein, 0610010I13Rik Protein, AI314617 Protein, BC019483 Protein, CSE Protein, Cys3 Protein, cysA Protein, SCQ11.03c Protein, DDBDRAFT_0190313 Protein, DDBDRAFT_0191318 Protein, DDB_0190313 Protein, DDB_0191318 Protein, H Protein, MGC75946 Protein, cystathionine gamma-lyase Protein, solute carrier family 2 member 1 Protein, cystathionase (cystathionine gamma-lyase) Protein, cystathionine gamma-lyase L homeolog Protein, CTH Protein, SLC2A1 Protein, cth Protein, Cth Protein, SCO3920 Protein, mlr1566 Protein, TA_RS00415 Protein, MAP_RS15640 Protein, SPO3344 Protein, CNN01730 Protein, Mmcs_1928 Protein, RHA1_RS31820 Protein, HNE_1212 Protein, MAV_3867 Protein, MSMEG_2394 Protein, Mvan_2142 Protein, SACE_6136 Protein, Mflv_4220 Protein, cysA Protein, cth.L Protein

Sujet: Recombinant Human Cystathionine γ-Lyase/CTH is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser405) of Human CTH.
Cystathionine γ-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.

Poids moléculaire: 44.7kDa

UniProt: P32929

Pathways: ER-Nucleus Signaling, L'effet Warburg